Protein conjugates for the diagnosis of Alzheimer’s disease
Development of specific imaging nanoprobes against intracerebral targets is a challenging field of research, particularly for the diagnosis of neurodegenerative diseases. Probes based on camelid single-domain antibody-fragments (VHHs or nanobodies) are promising tools due […]
A synthetic glycopeptide for anti-tumor immunotherapy: from design to first use in human
Within the framework of developing a carbohydrate-based vaccine against cancer, we designed and prepared the MAG-Tn3, a fully synthetic immunogen based on the tumor-associated Tn antigen. The MAG-Tn3 is a glycopeptide associating Tn clusters […]
2013Mucin-like peptides from Echinococcus granulosus induce antitumor activity, Int. J. Oncol. 2013 Sep;43(3):775-84.
2013MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion, J. Leukoc. Biol. 2013 Aug;94(2):315-23.
2013Specific IgG response against Mycobacterium avium paratuberculosis in children and adults with Crohn’s disease, PLoS ONE 2013;8(5):e62780.
2013Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer, Cancer Immunol. Immunother. 2013 Jun;62(6):1107-22.
2012A Tn antigen binding lectin from Myrsine coriacea displays toxicity in human cancer cell lines, J Nat Med 2013 Apr;67(2):247-54.
2010Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses, J. Biol. Chem. 2011 Mar;286(10):7797-811.
2010Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant, Blood 2010 Nov;116(18):3526-36.
2008The Pta-AckA pathway controlling acetyl phosphate levels and the phosphorylation state of the DegU orphan response regulator both play a role in regulating Listeria monocytogenes motility and chemotaxis, Mol. Microbiol. 2008 Dec;70(6):1342-57.
2008Cinnamic acid, an autoinducer of its own biosynthesis, is processed via Hca enzymes in Photorhabdus luminescens, Appl. Environ. Microbiol. 2008 Mar;74(6):1717-25.
2007Lipopentapeptide induces a strong host humoral response and distinguishes Mycobacterium avium subsp. paratuberculosis from M. avium subsp. avium, Vaccine 2008 Jan;26(2):257-68.
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