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Responsable de Structure
Groupe: Dégradation de l’ARN et traduction
Groupe: Micheline Fromont-Racine
Multiple Roles of RNAs
I have been appointed in 2013 Co-director together with Pr Yannick Andéol of the Multiple Role of RNAs Pasteur course. This two-week theorical and practical course presents RNA related technics (RNA seq, Northern blot […]
2017-02-13 00:01:10 2017-02-25 18:00:00 Europe/Paris Multiple Roles of RNAs I have been appointed in 2013 Co-director together with Pr Yannick Andéol of the Multiple Role of RNAs Pasteur course. This two-week theorical and practical course presents RNA related technics (RNA seq, Northern blot […] 28 Rue du Docteur Roux, Paris, France
S. cerevisiae gene regulation in quiescence
Gwenaël Badis-Breard (PI)
In wild life, yeast cells are able to survive in severe conditions, without nutriment for a long period of time because the cell is able to enter in stationary phase. During this phase, the […]
A personal database system for large scale quantitative results exploration (Cassandre, PTR 463)
Christophe Malabat (PI)
Cassandre is a project of personal database system, integrating a “user-friendly” interface to manage and explore multiple sets of large-scale experimental results in biology. Large-scale experiments that generate quantitative data, such as changes in […]
Quality Control at the Ribosome
Micheline Fromont-Racine (PI)
Gene expression is controlled and regulated by nuclear and cytoplasmic surveillance mechanisms in order to preserve the integrity of genetic information. Some of the mechanisms occur in the nucleus during transcription and maturation of […]
Diversity and stability of eukaryotic transcripts
Alain Jacquier (PI)
We focus on RNA quality control mechanisms and their consequences for the cells. Our previous studies revealed, for example, unexpected properties of the transcription process, such as its high pervasiveness and the intrinsic bi-directionality […]
Non-sense mediated mRNA decay mechanisms
Cosmin Saveanu (PI)
Non-sense mediated mRNA decay (NMD) is a fundamental and conserved mechanism with a major role in shaping the levels of individual RNAs in a eukaryotic cell by efficiently removing RNAs in which a stop […]
Genome-wide genetic screens by GIM (Genetic Interactions Mapping)
Cosmin Saveanu (PI)
To explore the effects of combining mutations and thus, be able to better understand complex functional interactions in a cell, we developed a novel genetic screening method that combines the exhaustivity of the yeast […]
2019A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes, EMBO J. 2019 Jun;.
2019Structure of the 80S ribosome-Xrn1 nuclease complex, Nat. Struct. Mol. Biol. 2019 Apr;26(4):275-280.
2018Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes, EMBO J. 2018 Oct;.
2018UPF1-like helicase grip on nucleic acids dictates processivity, Nat Commun 2018 Sep;9(1):3752.
2018Antisense transcriptional interference mediates condition-specific gene repression in budding yeast, Nucleic Acids Res. 2018 May;.
2018Short genome report of cellulose-producing commensal 1094, Stand Genomic Sci 2018;13:13.
2017The Gut Microbiota Facilitates Drifts in the Genetic Diversity and Infectivity of Bacterial Viruses, Cell Host Microbe 2017 Nov;.
2017MybA, a transcription factor involved in conidiation and conidial viability of the human pathogen Aspergillus fumigatus, Mol. Microbiol. 2017 Sep;105(6):880-900.
2017The ribosome-bound quality control complex: from aberrant peptide clearance to proteostasis maintenance, Curr. Genet. 2017 May;.
2017Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae, Sci. Rep. 2017 Mar 17;7:44761. doi: 10.1038/srep44761.
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25-28 Rue du Docteur Roux