The TherapUsher project funded by Retina-France is aimed at creating appropriate animal models for the USH1 retinal dystrophy.The Usher syndrome (USH) is the most prevalent cause of inherited deaf-blindness in humans. Three clinical subtypes, […]

TherapUsher

The TherapUsher project is aimed at creating appropriate animal models for the USH1 retinal dystrophy.The Usher syndrome (USH) is the most prevalent cause of inherited deaf-blindness in humans. Three clinical subtypes, USH1-3, have been […]

RHU LIGHT4DEAF

The enlightenment of the deafness: an holistic approach of Usher syndromeRecherche Hospitalo-Universitaire en SantéLIGHT4DEAF is coordinated by Professor José-Alain Sahel (Institut de la vision, Inserm, UPMC,CNRS), Professor Christine Petit (Institut Pasteur, Collège de France, […]

HearDeafTreat Hearing and deafness: molecular mechanisms and therapeutic approaches

Pr Christine PETIT was the coordinator of this 36 month project which included Pr E. Sylvester Vizi and Dr Tibor Zelles (partners from Institute of experimental medicine, Hungarian Academy of Science, Budapest, Hungary) as […]

SEIZEAR Cellular and molecular aspects of audiogenic seizures in Vlgr1‐/‐ mice.

Mutations in the gene encoding Vlgr1 (Very large G-coupled Receptor protein 1) areresponsible for Usher Syndrome type 2C (USH2C). This autosomal recessive syndrome is characterized by congenital, moderate to severe hearing impairment and a […]

LABEX LIFESENSES

Programme Grands investissements d’avenirSensory disorders significantly impact cognition, education, employment, autonomy and are associated with a heavy socio-economic burden (e.g. the combined cost of visual and auditory impairment is estimated at 600 billion Euros). […]

ERC-2011-AdG HAIRBUNDLE

Assembling the puzzle of the operating auditory hairbundleThe hair bundles of the sensory cells play a central role in the processing of sounds by the cochlea. Various performances of auditory perception depend upon what […]

Human and mouse hereditary deafness

Human and mouse hereditary deafness Severe to profound deafness affects one in 700 newborns. This disability also affects an additional one child in 1000 before adulthood, and 2.3% of the general population between 60 […]

From genes to the molecular physiology of hearing

All genes that we have identified as associated with deafness, except for the gene encoding pejvakin which is responsible for DFNB59, lead to a primary deficit in the peripheral auditory sensory system. An in-depth […]

Human and mouse hereditary deafness

Severe to profound deafness affects one in 700 newborns. This disability also affects an additional one child in 1000 before adulthood, and 2.3% of the general population between 60 and 70. Moreover, 40% of […]

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Published on: 16 Sep 2014 • Modified on: 18 May 2016