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2023Novel Antiviral Molecules against Ebola Virus Infection., Int J Mol Sci 2023 Sep; 24(19): .
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2020Retinoic Acid Inducible Gene I and Protein Kinase R, but Not Stress Granules, Mediate the Proinflammatory Response to Yellow Fever Virus, Journal of Virology, 2020, 94 (22), pp.e00403-20. ⟨10.1128/JVI.00403-20⟩.
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2017Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT, Sci Rep. 2017 Nov 23;7(1):16129.
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2015Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline, J Psychiatry Neurosci 2015 May;40(3):151-61.
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2014HIV-1 translation and its regulation by cellular factors PKR and PACT, Virus Res. 2014 Nov;193:65-77.
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2012dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection, Viruses 2012 Nov;4(11):2598-635.
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2011Hepatitis C virus reveals a novel early control in acute immune response, PLoS Pathog. 2011 Oct;7(10):e1002289.
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2010Hepatitis C virus controls interferon production through PKR activation, PLoS ONE 2010;5(5):e10575.
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2010ER targeting and retention of the HCV NS4B protein relies on the concerted action of multiple structural features including its transmembrane domains, Mol. Membr. Biol. 2010 Jan;27(1):45-62.
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2009Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS, J. Biol. Chem. 2009 Aug;284(33):21797-809.
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2007Lipoprotein lipase mediates hepatitis C virus (HCV) cell entry and inhibits HCV infection, Cell. Microbiol. 2007 Oct;9(10):2445-56.
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2007Cutting Edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells, J. Immunol. 2007 Mar;178(6):3368-72.
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2006The protein kinase IKKepsilon can inhibit HCV expression independently of IFN and its own expression is downregulated in HCV-infected livers, Hepatology 2006 Dec;44(6):1635-47.
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2006A hepatitis C virus (HCV) NS3/4A protease-dependent strategy for the identification and purification of HCV-infected cells, J. Gen. Virol. 2006 Dec;87(Pt 12):3587-98.
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2006The N-terminus of PKR is responsible for the activation of the NF-kappaB signaling pathway by interacting with the IKK complex, Cell. Signal. 2006 Nov;18(11):1865-75.
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2005Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon, J. Virol. 2005 Apr;79(7):3969-78.
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2004Positive effect of the hepatitis C virus nonstructural 5A protein on viral multiplication, Arch. Virol. 2004 Jul;149(7):1353-71.
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2002The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR, J. Biol. Chem. 2003 Feb;278(7):4440-8.
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2002The role of the phosphorus BI-BII transition in protein-DNA recognition: the NF-kappaB complex, Nucleic Acids Res. 2002 Oct;30(20):4452-9.
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2002Variability of the nonstructural 5A protein of hepatitis C virus type 3a isolates and relation to interferon sensitivity, J. Infect. Dis. 2002 Mar;185(5):573-83.
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2001Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression, J. Biol. Chem. 2001 Sep;276(36):33899-905.
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20001H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein, C. R. Acad. Sci. III, Sci. Vie 2000 Oct;323(10):883-94.
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2000PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex, Mol. Cell. Biol. 2000 Jul;20(13):4532-42.
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2000Expression of hepatitis C virus proteins interferes with the antiviral action of interferon independently of PKR-mediated control of protein synthesis, J. Virol. 2000 Jun;74(12):5587-96.
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2000Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways, Mol. Cell. Biol. 2000 Jan;20(2):617-27.
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1999Full peptide synthesis, purification, and characterization of six Tat variants. Differences observed between HIV-1 isolates from Africa and other continents, J. Biol. Chem. 1999 Apr;274(17):11473-8.
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1996Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons, J. Biol. Chem. 1996 Oct;271(41):25479-84.
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1995Human PKR transfected into murine cells stimulates expression of genes under control of the HIV1 or HTLV-I LTR, Virology 1995 Dec;214(2):653-9.
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1995Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase, J. Biol. Chem. 1995 Jul;270(29):17423-8.
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1995Nuclear localization of the interferon-inducible protein kinase PKR in human cells and transfected mouse cells, Exp. Cell Res. 1995 May;218(1):17-27.
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1994Characterization of an interferon-induced 48-kD protein immunologically related to the double-stranded RNA-activated protein kinase PKR, J. Interferon Res. 1994 Oct;14(5):251-7.
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1993Molecular cloning of two new interferon-induced, highly related nuclear phosphoproteins, J. Biol. Chem. 1993 Nov;268(32):24432-41.
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1993Localization of the human interferon-induced, ds-RNA activated p68 kinase gene (PRKR) to chromosome 2p21-p22, Genomics 1993 Jun;16(3):768-70.
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1993Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase, Proc. Natl. Acad. Sci. U.S.A. 1993 Jan;90(1):232-6.
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1992Detection of protein kinase homologues and viral RNA-binding domains utilizing polyclonal antiserum prepared against a baculovirus-expressed ds RNA-activated 68,000-Da protein kinase, Virology 1992 Dec;191(2):670-9.
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1992Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth, J. Virol. 1992 Oct;66(10):5805-14.
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1992Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2, EMBO J. 1992 Apr;11(4):1553-62.
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1991Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system, Mol. Cell. Biol. 1991 Nov;11(11):5497-505.
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1991Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli, Biochemistry 1991 Oct;30(42):10356-61.
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1990Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon, Cell 1990 Jul;62(2):379-90.
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1988Alpha-interferon inhibits the expression of heavy chain mu messenger RNA in Daudi cells, EMBO J. 1988 Jun;7(6):1689-96.
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1987Rapid decrease in the levels of the double-stranded RNA-dependent protein kinase during virus infections, Virology 1987 Jul;159(1):126-36.
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1985The 2-5A system in control and interferon-treated K/BALB cells infected with encephalomyocarditis virus, Prog. Clin. Biol. Res. 1985;202:307-15.
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1984Purification of the major species of human leucocyte interferon with the help of a monoclonal antibody, Dev. Biol. Stand. 1984;57:305-10.
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1982Use of an anti-human leukocyte interferon monoclonal antibody for the purification and radioimmunoassay of human alpha interferon, Infect. Immun. 1982 Sep;37(3):919-26.
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1981Interferon-mediated antiviral state in human MRC5 cells in the absence of detectable levels of 2-5A synthetase and protein kinase, J. Interferon Res. 1981 Feb;1(2):219-32.
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1980Antiviral response and induction of specific proteins in cells treated with immune T (type II) interferon analogous to that from viral interferon (type I)-treated cells, Virology 1980 Jul;104(1):195-204.
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1979Prophage substitution and prophage loss from superinfected Escherichia coli recA(P1) lysogens, J. Virol. 1979 Aug;31(2):277-80.
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1979Increased nuclease activity in cells treated with pppA2’p5’A2’p5′ A, Proc. Natl. Acad. Sci. U.S.A. 1979 Jul;76(7):3261-5.