The recent development of single-cell genetic and genomic technologies has a profound impact on all fields of biology by opening new avenues to study biological processes at the level of their fundamental unit, the cell. Those technologies enable to identify and characterise rare cell populations within organs or even whole organisms, to reconstruct dynamic states and trajectories adopted by cells along their life, both during embryonic development or in response to disease conditions or environmental factors. They can also identify the genes and the regulatory networks that govern cell identities in complex and changing environments.
The Pasteur Single Cell Initiative aims to foster the development of those transforming technologies at Pasteur and throughout the RIP. It brings high-throughput, cost-effective and widely applicable single-cell approaches to the broadest possible Pasteur user-base by providing opened technological pipelines for user-driven access and on-site development of novel applications.
• Technologies available
MARS-Seq robotic pipeline
10xGenomics Chromium unit
• Request of interest in conducting an experiment.
document: User support form
This Initiative is jointly developed by the research unit (Epi)genomics of Animal Development (Heather Marlow) and Citech (Elodie Brient-Litzler), supported by the Pasteur Flow Cytometry, Imagopole and Biomics platforms and C3BI.