Présentation
With the technological support of facilities at the Pasteur Institute and through collaborations with several international institutions, we study the early steps of signaling induced by interleukin-7 on CD4 T lymphocytes (helper). This cytokine is the main regulator, in lymphoid tissues as well as in the peripheral compartment, of differentiation, activation, survival and proliferation of CD4 T cells that coordinate the immune surveillance and response to infections and tumors.