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MOOC on biomarker
Biomarkers are the subject of considerable interest by scientists and researchers worldwide: they determine the use of targeted treatments (a major therapeutic advance in medicine), allow to measure the evolution of a disease or […]
2017-05-29 09:00:00
2017-07-12 18:00:00
Europe/Paris
MOOC on biomarker
Biomarkers are the subject of considerable interest by scientists and researchers worldwide: they determine the use of targeted treatments (a major therapeutic advance in medicine), allow to measure the evolution of a disease or […]
Institut Pasteur, Rue du Docteur Roux, Paris, France
Projets Transversaux
Projets
CV
(EN)
Medico-Scientific Career
- MD, University Paris Descartes (1983) : hepatitis B virus occult infections
- PhD, University Paris VII (1992) : regulation of iso-enzymes of ALT in liver disease
- HDR: University Paris Descartes (1997)
- Hepatology and Gastroenterology residency,
- Chief residency at the Necker-Enfants Malades University and
- Molecular enzymology fellowship in Henri Mondor hospital.
- Head of the Liver Department at Necker Hospital (2004-2006) and Cochin Hospital (after 09.2006)
- Head of group 36 Inserm U1016, Cochin Institute
- Institut Pasteur: co-director of UMS20 since April 2014
- Head of the center of Translational Research (January 2015)
Collective activities
- ANRS/Inserm: Head of AC24 (therapeutic trials)(2000-2005)
- PI of the Hepather cohort (>2012)
- director of the Center of Translationnal Research of Institut Pasteur since 2015.
Publications
Télécharger-
2019Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth, Nat. Immunol. 2019 Mar;20(3):257-264.
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2018Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus, Gut 2018 Nov;67(11):2017-2024.
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2017An in vitro diagnostic certified point of care single nucleotide test for IL28B polymorphisms, PLoS ONE 2017;12(9):e0183084.
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2017Hepatitis E virus-induced primary cutaneous CD30(+) T cell lymphoproliferative disorder, J. Hepatol. 2017 Dec;67(6):1334-1339.
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2016Immunological and Antiviral Responses After Therapeutic DNA Immunization in Chronic Hepatitis B Patients Efficiently Treated by Analogues, Mol. Ther. 2014 Mar;22(3):675-684.
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2016HCVerso1 and 2: faldaprevir with deleobuvir (BI 207127) and ribavirin for treatment-naïve patients with chronic hepatitis C virus genotype-1b infection, Clin Exp Gastroenterol 2016;9:351-363.
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2016Treatment With Ledipasvir-Sofosbuvir for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic Hepatitis C Virus Genotype 1 or 4 Infection: A Randomized Trial, Ann. Intern. Med. 2017 Jan;166(2):109-117.
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2016Hepatitis B virus reactivation in patients with solid tumors receiving systemic anticancer treatment, Ann. Oncol. 2016 Dec;27(12):2172-2184.
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2016Risk of cirrhosis-related complications in patients with advanced fibrosis following hepatitis C virus eradication, J. Hepatol. 2016 Oct;.
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2016Antiviral Treatment of HCV-Infected Patients with B-Cell Non-Hodgkin Lymphoma: ANRS HC-13 Lympho-C Study, PLoS ONE 2016;11(10):e0162965.
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