Cellular and molecular immunoprofiling of multiple sclerosis patients
This project aims at providing new knowledge on the immunomodulatory effect of IFN-I in multiple sclerosis patients by using state-of-the-art technologies. An important challenge is the identification of cellular and molecular biomarkers of IFN […]
Role of IFN-I in the development of IL-10-producing CD4 T cells
We have shown that IFN-I promotes development of human type 1 regulatory-like cells (Tr1) that produce the anti-inflammatory cytokine IL-10, and have studied the integration of T cell receptor (TCR) signal strength and CD28 […]
2011Differential role for CD277 as a co-regulator of the immune signal in T and NK cells, Eur. J. Immunol. 2011 Dec;41(12):3443-54.
2011PD-L2 is expressed on activated human T cells and regulates their function, Mol. Immunol. 2011 Sep;48(15-16):2214-9.
2010B and T lymphocyte attenuator is highly expressed on CMV-specific T cells during infection and regulates their function, J. Immunol. 2010 Sep;185(6):3140-8.