Epi-Med: synthesis and biological evaluation of new active molecules against MLL-rearranged leukaemia.
Rearranged Mixed Lineage lLukaemia (MLLr) is a form of leukaemia representing approximately 75% of paediatric acute leukaemia and 10% of adult leukaemia (AML and ALL), with a very poor prognosis of survival at 5 […]
2021Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein, Bon, C.et al. Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein. Molecules 2021, 26 (17), 5300. https://doi.org/10.3390/molecules26175300..