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This workshop provided three days of up to date training in experimental and comparative pathology. The program explored mouse models of cancer, diseases of the skin, muscle, bone, special senses, and immune system. It […]
2015-06-16 14:00:00 2015-06-19 Europe/Paris Mousepath 2015 This workshop provided three days of up to date training in experimental and comparative pathology. The program explored mouse models of cancer, diseases of the skin, muscle, bone, special senses, and immune system. It […] Institut Pasteur, Rue du Docteur Roux, Paris, France
Role of FAM13A in cystic fibrosis
Laurence Fiette (PI)
Cystic Fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). In this disease, among other consequences. The lung dysfunction remains the major cause of morbidity and […]
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Laurence Fiette (PI)
Diffuse intrinsic pontine gliomas (DIPG) represent the most agressive form of brain cancer and the third most common malignant brain tumor in children. The location of these tumors in the brainstem and the very […]
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Eliette Touati (PI)
The usptream stimulating factors USF1 and USF2 are pleïotropic transcription factors belong to the bHLH-Zip family as the oncogene c-Myc. They act as homo- or heterodimers and interact with DNA consensus E-box sequences in […]
PTR 496 – Investigating the reciprocal relationship between macrophage inflammasome activity and intracellular Leishmania infection
Eric Prina (PI)
Our proposal aims to decipher novel subversion strategies used by Leishmania (i) to withstand, circumvent or inhibit anti-microbial activities of host macrophages and (ii) to interfere with the induction of Leishmania-specific immune responses. We […]
2014: Accreditation to supervise research (HDR), Université Paris-Est Créteil, France
1996: PhD in Virology, University Paris VII, France
1990: Course on Fundamental Virology, Institut Pasteur, Paris, France
1990: Diplôme d’Etudes Spécialisées (DES) in Veterinary pathology
1988: C.E.S. Histology, Hematology and Pathology of Laboratory Animals, France
1987: Doctor in Veterinary Medicine, National Veterinary School of Alfort, France
AREAS OF SPECIALIZATION
Experimental pathology, comparative pathology Host-pathogens interactions Animal models
2004-2006: Head of the Platform of Veterinary Diagnosis (PDV), Geneva, Switzerland
I created the PDV in 2004 as part of the SVS (Science, Vie, Société) federal scientific project of the Lemanic academic research sites. The Platform provides expertise in experimental pathology to researchers, performs health monitoring of laboratory animals in the academic animal facilities and contributes to teaching and continuing education of researchers.
1996-2004: Senior Researcher (Chargée de Recherches)
URE Histotechnology and Pathology, Institut Pasteur, Paris, France
1992-1996: Assistant, Unit of Slow Viruses, Institut Pasteur, Paris
2015: Course on animal experimentation: Anatomy of Rodents and lagomorphs 2002-present: Master 2, Sciences du Médicament, Université Paris V-Descartes, Necropsy and sampling in Rodents
2002-2009: Co-director of the European Courses on the Pathology of Laboratory Animals : EuroGEMS (Pathology and Embryology of Genetically Engineered Mice), EuroPOLA (Spontaneous Pathology of Laboratory Animals), EuroTOXPATH (Toxicologic Pathology)
2000-2003: Co-director of the DIU (Master’s equivalent) of Morphological Analysis of Genetically Modified Rodents. Necropsy, Normal histology of rodents
President (elected) of the Scientific Council of the National Veterinary School of Alfort, France
Coordinator of the Pathex Network,
This network was created by the Comité d’interface Inserm-Anatomie et Cytologie pathologiques in 2010 to facilitate networking of people (researchers, students, engineers, technicians) working with animal models of human diseases firstname.lastname@example.org
Co-organiser of the Workshop Mousepath 2015, Institut Pasteur
Organiser of the Pathex scientific meetings, Institut Pasteur (Animal Models of Renal Diseases 2013, Nervous Diseases 2014, Skin Diseases 2015) 2012, 2014, 2016 Scientific Committee, Wellcome Trust Advanced Courses, Cambridge, UK, Mouse Models of Disease PROFESSIONAL AFFILIATIONS
President (elected) of the French Society of Veterinary Pathology (SFAPV)
Member of the Comité d’Interface INSERM-Anatomie Pathologique
2016Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle, Cell Stem Cell 2017 03;20(3):407-414.e4.
2016A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugs., Sci Rep. 2016 Oct 12;6:35025. doi: 10.1038/srep35025..
2016In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models., J Autoimmun. 2016 Oct 10. pii: S0896-8411(16)30183-4..
2015Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress, Carcinogenesis 2016 Jan;37(1):39-48.
2015Dissociation of Tissue Destruction and Bacterial Expansion during Bubonic Plague, PLoS Pathog. 2015 Oct;11(10):e1005222.
2015Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy, Nat. Immunol. 2015 Aug;16(8):850-8.
2015Impact of corticosteroids on experimental meningococcal sepsis in mice, Steroids 2015 Sep;101:96-102.
2014Protective role of LGP2 in influenza virus pathogenesis, J. Infect. Dis. 2014 Jul;210(2):214-23.
2013Neutrophils mediate antibody-induced antitumor effects in mice, Blood 2013 Oct;122(18):3160-4.
2013Aedes mosquito saliva modulates Rift Valley fever virus pathogenicity, PLoS Negl Trop Dis 2013;7(6):e2237.
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