CDPhages – ANR JCJC
Clostridium difficile (CD), recently reclassified as Clostridioides difficile, a Gram-positive spore-forming anaerobic bacterium, has rapidly emerged as the leading cause of antibiotic-associated diarrheal disease in hospitals worldwide. The incidence and severity of CD infections […]
Prophage elements as a significant source of genetic diversity among epidemic C. difficile 027 strains
The capacity to rapidly and accurately identify virulent strains of C. difficile in order to prevent severe and fatal infections remains a major chal- lenge for clinicians and investigators. Also, the evolution of an […]
2017High prevalence and genetic diversity of large phiCD211/phiCDIF1296T-like prophages in Clostridioides difficile, Appl. Environ. Microbiol. 2017 Nov;.
2017PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data, Sci Rep 2017 Aug;7(1):8292.
2015Factors Associated With Complications of Clostridium difficile Infection in a Multicenter Prospective Cohort, Clin Infect Dis. 2015 Dec 15;61(12):1781-8.
2014Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins, Appl Environ Microbiol. 2014 Apr;80(8):2555-63.
2014Prevention of Clostridium difficile spore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam, BMC Infect Dis. 2014 Jan 15;14:29.