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(EN)
FAURE Grazyna, PhD, HDR
Curriculum Vitae
Birth place: Stalowa Wola, Poland
Current Position: Chargée de Recherche Expert (Research Scientist) in Pasteur Institute
Address: Institut Pasteur, Unité Récepteurs-Canaux, Departement Neurosciences, 25, rue du Dr Roux, 75724 Paris, France
University diplomas
1983 Ph.D. in Biochemistry, University of Paris VI (UPMC)
2001 HDR, University René Descartes of Paris V
Distinction
2014 “Visiting Professor” in Department of Biochemistry of the Nicolaus Copernicus University in Torun (Poland)
Memberships:
International Society of Toxinology (IST)
Societé Française pour l’Etude des Toxines (SFET) (Administration Council 2012-2018)
Teaching responsibilities and training:
1996 – 2016: Lectures for Master 2 “Molecules et cibles therapeutiques” UPMC and Muséum National d’Histoire Naturelle in Paris
1999 – 2017: Lectures for “Venomous and Venenous Animals” Courses in MNHN
Scientific expert of Surface Plasmon Resonance technology in Pasteur Institute
Research director of 28 students.
Peer-reviewing for:
European Journal of Biochemistry; Biochimie; Toxicon; Biochemical Journal; BBA; Biochem. Biophys. Res. Comm.; FEBS Journal; Journal of Proteome Res.; Journal of Immunol. Meth.; Journal of Liquide Chromat & Rel. technologies; Comparatives Biochem.& Physiol; Intern. J. of Biochem & Cell Biol
Total number of publications:
Author of 78 publications with international committees. Participation to 160 congresses with more than 40 invitations as speaker around the world.
Patent
Faure, A. Edelman, N. Odolczyk, P. Zielenkiewicz
WO 2017/187274 A1
PCT/FR2017/051030 Methods and compositions for modifying cystic fibrosis transmembrane conductance regulator activity, déposée le 28 avril 2017 sous la priorité de la demande de brevet américain provisoire US 62/329,875 déposée le 29 avril 2016 aux noms de l’Institut Pasteur, l’INSERM et l’IBB -Academy of Sciences de Varsovie.
Publications
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2017Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors, Sci Rep 2017 Nov;7(1):16606.
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2017Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors, PLoS ONE 2017;12(10):e0186206.
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2017New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8, Protein Sci. 2017 Feb;26(2):343-354.
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2016Interaction of three-finger proteins from snake venoms and from mammalian brain with the cys-loop receptors and their models, Dokl. Biochem. Biophys. 2016 May;468(1):193-6.
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2016Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis, J. Mol. Biol. 2016 Jul;428(14):2898-915.
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2016Special Issue on “Toxins: New targets and new functions”, Toxicon 2016 Jun;116:1-3.
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2016Neurotoxic phospholipase A2 from rattlesnake as a new ligand and new regulator of prokaryotic receptor GLIC (proton-gated ion channel from G. violaceus), Toxicon 2016 Jun;116:63-71.
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2016[Relationships between venomous function and innate immune function], Biol Aujourdhui 2015;209(3):195-210.
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2013Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain, EMBO Mol Med 2013 10;5(10):1484-501.
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2012Crystallographic characterization of functional sites of crotoxin and ammodytoxin, potent β-neurotoxins from Viperidae venom, Toxicon 2012 Sep;60(4):531-8.
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