What’s best to study humans and their infectious deseases than Human emulation system ? It’s now possible at Pasteur to develop real Organs-on-chips with cells from different sources, patient derived or cell line. At […]
Endocytosis: the clathrin-independent uptake of cytokine receptors
Endocytosis is an essential process used to internalize a wide range of molecules, and involved in many processes such as cell migration, cell division, immunity and pathogen invasion. Several endocytic pathways exist, enabling the […]
Exocytosis: inhibition of secretion/recycling by the pathogen Shigella
The distribution of cholesterol – in a gradient – is essential for compartments organization. Cholesterol distribution within the organelles should be tightly controlled but so far little is known on the dynamics its intracellular […]
Welcome to the club! Welcome to Microfluidics@Pasteur! Our goal is to serve as the major entry point to all the scientists on the campus (beginners and experts) interested in undertaking projects where microfluidics is involved. Our […]
2019Bioengineered Human Organ-on-Chip Reveals Intestinal Microenvironment and Mechanical Forces Impacting Shigella Infection, Cell Host Microbe 2019 10;26(4):565.
2019promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport, Proc. Natl. Acad. Sci. U.S.A. 2019 Jul;116(27):13582-13591.