One ERC-funded postdoctoral position is available in the lab “Stroma, Inflammation and Tissue Repair” (Department of Immunology, Institut Pasteur, Paris) to study the regulation of immune responses and tissue repair by stromal cells.
Our lab investigates the role of stromal mesenchymal cells in tissue homeostasis and repair and how perturbation of stromal pathways impacts on inflammatory diseases and cancer (Dulauroy, Nature Medicine 2012; Stzepourginski, PNAS 2017; Di Carlo, JCI 2018). Using unique mice models developed in the lab, the aim of this project is to identify novel mechanisms that stromal cells employ to regulate tissue repair, with a focus on immune responses and the crosstalk to tissue stem cells. We are interested in different organs, including the intestine, skin and lymphoid organs.
The study will involve wide range of techniques including in vivo lineage tracing/ genetic depletion in mice models, multi-parametric flow cytometry, confocal microscopy and transcriptomic studies (RNAseq). This position is part of an ERC project aiming at identifying new therapeutic approaches in inflammatory diseases and cancer. For more information about our laboratory, please visit our website: https://research.pasteur.fr/en/team/group-lucie-peduto/.
The successful candidate has recently obtained a PhD (2019 or 2020) and has strong interest and a proven track record of achievement in immunology or tissue repair/mesenchymal biology. Motivated candidates with creative and innovative skills, which have previous experience with bioinformatics analysis of single cells/bulk RNAseq, FACS or confocal imaging are especially encouraged to apply. The Institut Pasteur in Paris offers an international, dynamic and stimulating scientific campus with more than 1500 researchers working in 11 Departments favouring multiple collaborations, and access to top-notch plateforms.
The position is available starting immediately, for one-year contract (renewable), and includes benefits according to French laws. To apply, please send your complete CV, motivation letter and contact information for 3 references, to: firstname.lastname@example.org.