Timeline

Yves Jacob
Group Leader
16 Jul 2020
project

Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)

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22 Oct 2019
event

Virology Department Seminar: “Mechanism of epigenetic variability in clonal cell lineages” with Alexander Gimelbrant

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07 Jun 2018
event

“Network Medicine: From Cellular Networks to the Human Diseasome” Virology & C3BI seminar with Albert-Lazlo Barabasi

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06 Feb 2018
publication

The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome

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23 Nov 2017
publication

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT

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11 Oct 2017
event

C3BI Seminar – Systems biology seminars

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13 Apr 2017
event

Pr Frederick P. ROTH – VIROLOGY DEPARTMENT SEMINAR

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20 May 2016
project

Role of PDZ-binding motif from Flavivirus non-structural proteins in flaviviral life cycle

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07 Sep 2015
tool

Optogenetic “Cre-stiching” strategy for barcode fusion genetics

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07 Sep 2015
tool

High-throughput protein-protein interaction assay based on a split-luciferase

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04 Sep 2015
project

Interplay between influenza virus and the ubiquitin/proteasome system

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04 Sep 2015
project

Multi-species mapping of influenza viruses cellular targets using high-throughput complementary strategies in a “One Health” perspective.

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04 Sep 2015
project

Comparative interactomics of filoviridae (Task Force Ebola WP6.2)

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18 Aug 2015
project

Design and optimization of new bioluminescent systems better-suited to in cellulo and in vivo conditions

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16 Jul 2015
team

Virus interactomics

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17 Jun 2015
publication

Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other

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08 Jun 2015
publication

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay

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27 May 2015
publication

Targeting the Two Oncogenic Functional Sites of the HPV E6 Oncoprotein with a High-Affinity Bivalent Ligand

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11 May 2015
team

Molecular Genetics of RNA Viruses

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23 Apr 2015
publication

Widespread macromolecular interaction perturbations in human genetic disorders

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01 Jan 2015
publication

A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions

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11 Dec 2014
publication

Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus

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01 Sep 2014
publication

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage

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12 Jun 2014
publication

Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing

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27 Nov 2013
publication

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication

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03 Oct 2013
publication

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

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18 Jul 2013
publication

A comparative approach to characterize the landscape of host-pathogen protein-protein interactions

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01 Jul 2013
publication

Exploration of binary virus-host interactions using an infectious protein complementation assay

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26 Apr 2013
publication

Species-specific impact of the autophagy machinery on Chikungunya virus infection

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21 Feb 2013
publication

EVER2 protein binds TRADD to promote TNF-α-induced apoptosis

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14 Jan 2013
publication

The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells

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16 Aug 2012
publication

Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly

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08 Aug 2012
publication

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase

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28 Jun 2012
publication

Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions

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13 Jun 2012
publication

HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication

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18 Jan 2012
publication

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component

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29 Nov 2011
publication

Benchmarking a luciferase complementation assay for detecting protein complexes

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17 Nov 2011
publication

Inhibition of influenza virus replication by constrained peptides targeting nucleoprotein

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12 Sep 2011
publication

The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism

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08 Dec 2009
publication

ViralORFeome: an integrated database to generate a versatile collection of viral ORFs

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18 Sep 2009
publication

Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor

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12 Aug 2009
publication

Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity

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22 Jun 2009
publication

Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS

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01 Jun 2009
publication

The EVER proteins as a natural barrier against papillomaviruses: a new insight into the pathogenesis of human papillomavirus infections

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12 Nov 2008
publication

Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2

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04 Nov 2008
publication

Hepatitis C virus infection protein network

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13 Oct 2008
publication

Monitoring of chloride and activity of glycine receptor channels using genetically encoded fluorescent sensors

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17 Jun 2008
publication

Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein

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05 Mar 2008
publication

Mitochondrial dysfunction in lyssavirus-induced apoptosis

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06 Jan 2008
publication

Genetically encoded chloride indicator with improved sensitivity

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01 Jan 2008
publication

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells

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24 Dec 2007
publication

Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses

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07 Aug 2007
publication

Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling

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07 Feb 2007
publication

Rabies virus matrix protein interplay with eIF3, new insights into rabies virus pathogenesis

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04 Oct 2006
publication

Human papillomavirus type 5 E6 oncoprotein represses the transforming growth factor beta signaling pathway by binding to SMAD3

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01 May 2006
publication

Cottontail rabbit papillomavirus E8 protein is essential for wart formation and provides new insights into viral pathogenesis

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01 Jan 2006
publication

Rabies: epidemiological tendencies and control tools

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17 Apr 2005
publication

A variant in the CD209 promoter is associated with severity of dengue disease

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01 Jul 2004
publication

Antiviral drug discovery strategy using combinatorial libraries of structurally constrained peptides

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15 Aug 2003
publication

Targeting of incoming retroviral Gag to the centrosome involves a direct interaction with the dynein light chain 8

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01 Feb 2002
publication

A novel expression cassette of lyssavirus shows that the distantly related Mokola virus can rescue a defective rabies virus genome

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01 Jan 2002
publication

Integrated version of reverse two-hybrid system for the postproteomic era

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01 Nov 2001
publication

Molecular basis for the interaction between rabies virus phosphoprotein P and the dynein light chain LC8: dissociation of dynein-binding properties and transcriptional functionality of P

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01 Jan 2000
publication

DNA-based immunisation against rabies and rabies-related viruses: towards multivalent vaccines

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