Timeline

Christian Muchardt
Head of Structure
07 Jun 2019
publication

The epigenetics of multiple sclerosis

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20 May 2019
event

Thesis Defense by Nowsheen Mullani: “An RNA Signature Links Oxidative Stress To Cellular Senescence”. Developmental and Stem Cell Biology Department/ Epigenetic Regulation Unit

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08 May 2019
publication

Expression of endogenous retroviruses reflects increased usage of atypical enhancers in T cells

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23 Nov 2018
event

Developmental and Stem Cell Biology seminar by Dr. Ritwick Sawarkar, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany

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11 Oct 2018
publication

HIBISCUS: HYDROXYCHLOROQUINE FOR THE SECONDARY PREVENTION OF THROMBOTIC AND OBSTETRICAL EVENTS IN PRIMARY ANTIPHOSPHOLIPID SYNDROME

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06 Jun 2018
publication

Primary antiphospholipid syndrome and antiphospholipid syndrome associated to systemic lupus: Are they different entities?

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21 Mar 2017
publication

Threonine eliminylation by bacterial phosphothreonine lyases rapidly causes cross-linking of mitogen-activated protein kinase (MAPK) in live cells

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02 Dec 2016
news

“Transposable elements, polydactyl proteins and the species-specificity of human biology”

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04 Oct 2016
news

SEMINAR ” RNA Therapeutics: Antisense Oligonucleotides for the Treatment of Degenerative Disorders “

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04 Oct 2016
news

SEMINAR ” Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T cell activation “

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23 Sep 2016
publication

A Broad Set of Chromatin Factors Influences Splicing

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10 Nov 2015
event

Pacific Biosciences Seminar by Kevin CORCORAN

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02 Nov 2015
news

SEMINAR ” Programming and Reprogramming Cell Fate “

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14 Sep 2015
project

Epigenetic regulation of alternative splicing

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14 Sep 2015
project

Role of RNA interference pathways in the alternative splicing regulation

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11 Sep 2015
project

iSPLICE: Regulation of alternative splicing by RNAi and non-coding RNAs

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11 Sep 2015
project

Silence to cure: stabilize chromatin for the management of diseases with inflammatory components

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08 Sep 2015
project

Dynamic regulation of chromatin and transcription by HP1 Heterochromatin Proteins in relationship with RNA.

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17 Jul 2015
project

The chromatin-remodeling complex SWI/SNF as a modulator of alternative splicing

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11 May 2015
team

Epigenetic Regulation

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11 May 2015
publication

Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors

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20 Jan 2015
publication

Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions

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16 Sep 2014
publication

The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

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12 Sep 2014
publication

Shigella flexneri targets the HP1γ subcode through the phosphothreonine lyase OspF

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12 May 2014
publication

DYRK1A phoshorylates histone H3 to differentially regulate the binding of HP1 isoforms and antagonize HP1-mediated transcriptional repression

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08 Aug 2013
publication

Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription

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12 Apr 2013
publication

10-million-years AGO: argonaute on chromatin in yeast and human, a conserved mode of action?

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28 Jan 2013
publication

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration

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13 Sep 2012
publication

Citrullination of histone H3 interferes with HP1-mediated transcriptional repression

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09 Sep 2012
publication

Argonaute proteins couple chromatin silencing to alternative splicing

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09 Aug 2012
publication

A novel Plasmodium falciparum SR protein is an alternative splicing factor required for the parasites’ proliferation in human erythrocytes

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01 Aug 2012
publication

The absence of Brm exacerbates photocarcinogenesis

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03 Jan 2012
publication

Inhibition of PP1 phosphatase activity by HBx: a mechanism for the activation of hepatitis B virus transcription

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27 Feb 2011
publication

Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons

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01 Feb 2010
publication

A few thoughts about catalyzing transcription

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11 Dec 2009
publication

Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression

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03 Aug 2009
publication

Human BAHD1 promotes heterochromatic gene silencing

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20 May 2009
publication

SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity

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15 May 2009
publication

The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation

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10 Apr 2009
publication

Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia

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03 Apr 2009
publication

Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification

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15 Dec 2008
publication

The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer

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26 Mar 2008
publication

Splicing, transcription, and chromatin: a ménage à trois

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01 Feb 2008
publication

Regulation of an inducible promoter by an HP1beta-HP1gamma switch

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03 Aug 2007
publication

Histone modifications induced by a family of bacterial toxins

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21 Feb 2007
publication

Coregulators: transducing signal from transcription to alternative splicing

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10 Dec 2006
publication

An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses

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15 May 2006
publication

Role for Brm in cell growth control

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11 Dec 2005
publication

The human SWI/SNF subunit Brm is a regulator of alternative splicing

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01 Sep 2005
publication

The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation

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01 May 2005
publication

SWI/SNF chromatin-remodeling factors induce changes in DNA methylation to promote transcriptional activation

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03 Sep 2004
publication

Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene

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01 Jul 2004
publication

Cyclin A repression in quiescent cells is associated with chromatin remodeling of its promoter and requires Brahma/SNF2alpha

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23 Apr 2004
publication

Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3

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15 Dec 2003
publication

Growth inhibition by the mammalian SWI-SNF subunit Brm is regulated by acetylation

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15 Jan 2003
publication

SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development

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13 Sep 2002
publication

Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1alpha

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01 Feb 2002
publication

SWI/SNF chromatin remodeling and cancer

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