Timeline

Allison Williams
Permanent Researcher
08 Jul 2019
publication

The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation

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08 Mar 2019
publication

Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase

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08 Mar 2019
publication

Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase

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26 Feb 2018
publication

A step-by-step guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase

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22 Feb 2017
publication

Bulgecin A: The Key to a Broad-Spectrum Inhibitor  That Targets Lytic Transglycosylases

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13 Feb 2017
publication

N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes

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02 Jan 2017
project

Inhibition of peptidoglycan assembly complexes

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14 Sep 2015
project

ERC-2007-Stg-202283-PGNfromSHAPEtoVIR

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02 Jul 2015
project

Biology and Genetics of Bacterial Cell Wall

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11 May 2015
team

Biology and Genetics of Bacterial Cell Wall

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27 Sep 2014
publication

Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members

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15 Nov 2013
publication

The dynamics of peptidoglycan structure and function: conference report on the 3rd Great Wall Symposium

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03 Feb 2013
publication

De-O-acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis

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20 Mar 2012
publication

The effect of bulgecin A on peptidoglycan metabolism and physiology of Helicobacter pylori

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04 Nov 2011
publication

Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway

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07 Jul 2009
publication

Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA

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13 Aug 2007
publication

Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase

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11 Jul 2006
publication

Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide

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24 Mar 2004
publication

Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3″-hydroxyl group

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