Timeline
30 Jul 2016
publication
Buffering deleterious polymorphisms in highly constrained parts of HIV-1 envelope by flexible regions
Read more03 Jul 2015
18 Jun 2015
publication
A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity
Read more22 May 2014
publication
Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry
Read more21 May 2013
publication
HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines
Read more30 Apr 2013
publication
β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6
Read more01 Jan 2013
11 Jul 2012
publication
CCR5 mutations distinguish N-terminal modifications of RANTES (CCL5) with agonist versus antagonist activity
Read more20 Jul 2011
30 Nov 2010
publication
New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection
Read more20 Apr 2009
publication
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
Read more01 Aug 2008
publication
Cholesterol content drives distinct pharmacological behaviours of micro-opioid receptor in different microdomains of the CHO plasma membrane
Read more02 Jul 2008
publication
The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins
Read more13 Jun 2008
24 Apr 2008
publication
CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome
Read more01 Mar 2008
publication
Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling
Read more13 Sep 2007
publication
CD4 interacts constitutively with multiple CCR5 at the plasma membrane of living cells. A fluorescence recovery after photobleaching at variable radii approach
Read more29 Dec 2006
publication
Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and G(alpha)(i) activation
Read more11 Oct 2006
publication
CD4 and CCR5 constitutively interact at the plasma membrane of living cells: a confocal fluorescence resonance energy transfer-based approach
Read more17 Aug 2005
publication
The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
Read more10 Mar 2005
publication
Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis
Read more15 Dec 2004
publication
CXCR4-tropic HIV-1 envelope glycoprotein functions as a viral chemokine in unstimulated primary CD4+ T lymphocytes
Read more09 Nov 2004
publication
WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12
Read more03 Aug 2004
publication
Dynamic confinement of NK2 receptors in the plasma membrane. Improved FRAP analysis and biological relevance
Read more12 Nov 2002
publication
HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains
Read more23 Jan 2002
publication
Lateral distribution of cholesterol in membranes probed by means of a pyrene-labelled cholesterol: effects of acyl chain unsaturation
Read more14 Sep 2001
publication
Probing the lateral organization of membranes: fluorescence repercussions of pyrene probe distribution
Read more27 Oct 2000
publication