The Systems Biology group develops computational tools to help discover causal paths in complex diseases.
Our research is based on large datasets that characterize biological samples at different molecular and clinical levels, including molecular (e.g., transcriptomic, proteomic, and metabolomic) networks. Recently, gene expression data from single cells has started to give us even higher resolution.
By helping discovering causal paths, which sometimes differ between patients, we aim to help stratify, classify, predict, and treat, towards medicine that predicts and prevents instead of reacting. We collaborate with biological, medical, and technology experts here at Institut Pasteur, in France, and internationally.
Our group is probably best known for creating and developing Cytoscape, an open-source community platform to visualize and analyze molecular networks, which is today being developed around the world. We are also member of the national “laboratory of excellence” (LabEx) programs Milieu Intérieur and IBEID.
Since 2017, researchgate.net states more and more often that “our research items were the most cited research items from their institution”.