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About

The Lymphocytes and Immunity Unit, attached to the Immunology Department of the Institut Pasteur, was created on March 1st, 2020 and is the follow up of :

  • the Lymphopoiesis unit created in January 2011
  • the Unit for Lymphocyte Development created in 1998.

It joins the Inserm unit U1223 (previously U668) “Physiopathologie du Système Immunitaire” directed by James Di Santo. Since 2014, the Lymphocytes and Immunity unit is under contract with Université Paris Diderot.

figure_lymphopoiese.jpg

 

 

Members

Ana Cumano
Head of Structure
Head
Pablo Pereira Esteva
Permanent Researcher
Paulo Vieira
Group Leader
Rachel Golub
Group Leader
Marie-Christine Vougny
Administrative Staff
Delphine Guy-Grand
Retired scientist
Ramy Elsaid
Post-doc
Antonio Bandeira Ferreira
Permanent Researcher
Françoise Guinet
Permanent Researcher
Sylvain Meunier
Research Engineer
Nathan Mackowski
PhD Student
Marie-Pierre Mailhe
Technician
Elsa Bourayou
PhD Student
Dali AMIRI
Graduate Student
Marcia Peixoto
PhD Student
Francisca Soares Da Silva
PhD Student

Former Members

2000
2000
Name
Position
2015
2020
Damien Garrido
2015
2020
Jerome Van Wassenhove
2015
2020
Perpetua Pinto-do-Ó
Post-doc
2015
2020
Sylvestre Chea
Post-doc
2015
2020
Laurent Boucontet
Research Engineer
2015
2020
Sandrine Schmutz
Research Engineer
2015
2020
Khaoula Boulkrout
Undergraduate Student
2015
2020
Claire Berthault
Post-doc
2015
2020
Jean-Baptiste Beneteau
Undergraduate Student
2015
2020
Aleksandr Barinov
Post-doc
2015
2020
Jean-Pierre Jourdain
Technician
2015
2020
Lucia Orsini
Post-doc
2015
2020
Mélissa Maraux
Graduate Student
2015
2020
Emilia Chmielnicki
Graduate Student
2015
2020
Elena-Gaia Banchi
Undergraduate Student
2015
2020
Victoria Jacko-Reynolds
Undergraduate Student
2015
2020
Marta Santa Maria Tobias
Undergraduate Student
2015
2020
Julien Plisson
Undergraduate Student
2015
2020
Ioana Dobrota
Undergraduate Student
2015
2020
Ana Catarina Cardoso da Silva
PhD Student
2015
2020
Alix Jarraud
Undergraduate Student
2015
2020
Shahed Al-Bounny
Graduate Student
2015
2020
Robert Dieu
Graduate Student
2015
2020
Florian Specque
Undergraduate Student
2015
2020
Romane Brunet-Bietrix
Undergraduate Student
2015
2020
Luis Graca
Associate Professor
2015
2020
Junjie Yang
PhD Student
2015
2020
Sarah Soussan
Undergraduate Student
2015
2020
Sten-Eirik Jacobsen
Visiting Scientist
2015
2020
Amélie Grosjean
Undergraduate Student
2015
2020
Alia Bouhaouche
Undergraduate Student
2015
2020
Thibaut Perchet
Post-doc
2015
2020
Youssef MECHEHAR
Undergraduate Student
2015
2020
Elisa Dourado
Undergraduate Student
2015
2020
Odile Burlen-Defranoux
Research Engineer
2015
2020
Maxime Petit
PhD Student
2015
2020
Nabil Sadouni
Undergraduate Student
2020
2020
Ines Pereira
Undergraduate Student
Show all

Projects

Project
Ongoing
2 Members

Implication de la voie Notch et des cellules lymphoïdes innées lors d’un hépatocarcinome cellulaire

Rachel Golub (PI)

 
Project
Ongoing
6 Members

The role of lncRNA H19 in Thymopoiesis

Ana Cumano (PI)

“The thymus is a specialized organ that provides a unique environment for T cell development and differentiation. The study the thymus-settling progenitors (TSPs) and how they differentiate is important for the characterization of the […]
Project
Ongoing
2 Members

Genesis of the peripheral regulatory system.

Antonio Bandeira Ferreira (PI)

A fundamental concept on the development of the natural regulatory cells is that the thymus only exports regulatory T cells after the third day post-birth, implying a differential developmental program controlling the generation of […]
Project
Ongoing
6 Members

Innate lymphoid cell differentiation

Rachel Golub (PI)

We found that RoRgt expressing innate lymphoid cells (ILC) develop in the fetal liver but not in the bone marrow (BM). However, BM progenitors give rise to RoRgt+ILC in the peripheral lymphoid organs and […]
Project
Ongoing
2 Members

The role of a gradient of the chemokine CXCL12 in hematopoietic development and in a normal immune response. (Collaboration with F. Arenzana-Seisdedos, granted ANR funding)

Paulo Vieira (PI)

Interaction with heparan sulfate proteoglycans is supposed to provide chemokines with the capacity to immobilize on cell surface and extracellular matrix for accomplishing both tissue homing and signaling of attracted cells. The laboratory of […]
Project
Ongoing
6 Members

T cell development

Ana Cumano (PI)

We recently found (Ramond et al 2014, Nat Immunol) that the mouse thymus is colonized by successive waves of progenitors that differ in their developmental stage and function. Our observations show that the T […]
Project
Ongoing
3 Members

Deregulation of hematopoiesis by Interleukin-10 over-expression (Joint project with the University of Minho, Portugal, granted ANR international funding)

Paulo Vieira (PI)

Cytokines are soluble molecules that regulate a large array of developmental processes. In the hematopoietic system, cytokines mediate the production of mature blood cells from specific lineages, by directly acting on hematopoietic progenitors. Cytokines […]

Transversal Project

LabEx Milieu Intérieur

The Milieu Intérieur project provides insight into the core of human diversity by dissecting the interplay between genetics and environment and their impact on the immune system. The Milieu Intérieur Project While the immune […]

LabEx Revive – Regenerative biology & medicine

  Rationale and Objectives of Revive Consortium Major advancements in stem cell biology have paved the way for concerted research activities on the fundamental biology of stem cells and their applications in the clinic. […]

Fundings

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Contact

Tel 33 1 45 68 82 55 Secrétariat 33 1 45 68 85 93 Fax 33 1 45 68 89 21 Email: ana.cumano@pasteur.fr Adresse 25 Rue du Docteur Roux 75015, Paris France