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  • whocc
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  • Associate Professor
  • Clinical Research Assistant
  • Clinician Researcher
  • Department Manager
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Permanent Researcher
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  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
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About

Our Unit focuses on the following research topics:

  • Use of the Measles virus, a live-attenuated vaccine (LAV), as a platform to develop new vaccines, specifically against DENV, CHIKV, HIV, SARScoV and H5N1. The efficacy of this strategy in humans has been highlighted in recent clinical studies such as that by Ramsauer et al., The Lancet Infectious Diseases, 2015. (Group F. Tangy and Group N. Escriou).
  • Development of a high-throughput screening (HTS) assay allowing for the identification of the interaction between cellular proteins and viral proteins or RNA (Group A. Komarova).
  • Understanding the mechanisms of attenuation of LAVs, with a specific focus on those against Yellow fever virus and Measles virus (Group N. Jouvenet and Group A. Komarova).

 

Viral Genomics and Vaccination Unit_2016

Former Members

2000
2000
Name
Position
2015
2020
Luisa Mandorli
Undergraduate Student
2015
2020
Mégane Babiak
2015
2020
Roseline Vibert
Undergraduate Student
2015
2020
Daria Jacob
Post-doc
2015
2020
Maria Pereira
2015
2020
Monica Sala
Administrative Staff
2015
2020
Mariana Mesel-Lemoine
2015
2020
Daniela Bruni
Post-doc
2015
2020
Raul Sanchez David
Post-doc
2015
2020
Marie-Laurence Meignan
Administrative Staff
2015
2020
Stéphanie Woerner
Post-doc
2015
2020
Ho Hong Hai Vo
Post-doc
2015
2020
Marianne Lucas-Hourani
Research Engineer
2015
2020
Evgeniya Petrova
Post-doc
2015
2020
Laura Sinigaglia
PhD Student
2015
2020
Salomé Bourgeau
Undergraduate Student
Show all

Courses

08:00
26
Apr 2022
Course

Vaccinology MOOC

This MOOC describes the successes of vaccination in preventing diseases, as well as the remaining challenges in regard of persisting epidemics and new pandemics. Register on : https://www.fun-mooc.fr/en/courses/vaccinology/ Flyer : MOOC_VACCINOLOGY_2022 Vaccines are among the […]
Innovation lab : vaccines
Armelle Phalipon
Chloé Albert
2022-04-26 08:00:00 2022-06-26 23:00:00 Europe/Paris Vaccinology MOOC This MOOC describes the successes of vaccination in preventing diseases, as well as the remaining challenges in regard of persisting epidemics and new pandemics. Register on : https://www.fun-mooc.fr/en/courses/vaccinology/ Flyer : MOOC_VACCINOLOGY_2022 Vaccines are among the […]

Projects

Project
Ongoing
12 Members

HIV signature on RIG-I-like receptors

Anastasia V. Komarova (PI)

The pathogenesis of HIV infection, and in particular the development of immunodeficiency, remains incompletely understood. During HIV infection both innate and adaptive immune responses are raised, but they appear to be insufficient or too […]
Project
Completed
8 Members

Understanding viral attenuation for the rationalization of vaccine design

Nolwenn Jouvenet (PI)

Vaccination is one of the greatest successes of modern medicine. The first generation of viral vaccines relied on empiric attenuation by repeated passage in animals and/or cultured cells. A successful attenuation process eliminates virulence […]
Project
Ongoing
12 Members

Alkoxypyrazoles, inhibitors of dihydroorotate dehydrogenase (DHODH)

Yves Janin (PI)

A thousand fold improvement of an antiviral activity The starting point of this project was the modest activity displayed by compounds 1 and 2, on the phenotypic Measles-based antiviral assay designed by Pierre-Olivier Vidalain […]
Project
Ongoing
12 Members

Bivalent vaccines derived from measles vaccine

Frédéric Tangy (PI)

Bivalent vaccines derived from measles vaccine (F. Tangy, N. Escriou) Major childhood diseases, such as polio or measles, have been virtually eliminated since the 60s thanks to the use of live-attenuated vaccines. Today, millions […]

Transversal Project

Vaccinology and Immunotherapy initiative

Vaccines have had a major positive impact on public health world-wide through disease prevention that can be measured in millions of lives saved. Despite the successes, we still face major challenges in vaccine and […]

Cancer Initiative

With more than 19.3 million new cases in 2020 worldwide, including nearly 400,000 in France, cancer is a common disease that affects or will affect us all one day, directly or indirectly. It is […]

Emerging Infectious Diseases

Ever since its very early days, the Institut Pasteur has been committed to tackling emerging infections, and its work has left an extraordinary legacy. Many emerging infectious diseases are zoonoses, in which an animal […]

The institut Carnot Pasteur MS

Carnot, label of excellence Founded in 2006, the Carnot Label, granted by the French government, was designed to develop partnership-based research, meaning research conducted by public laboratories in partnership with socio-economic players, primarily industry […]

LabEx Milieu Intérieur

The Milieu Intérieur project provides insight into the core of human diversity by dissecting the interplay between genetics and environment and their impact on the immune system. https://www.youtube.com/watch?v=IXlKElDJMc8 The Milieu Intérieur Project While the […]

Publications

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Contact

Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France     Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France     Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France   Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France   Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France     Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France     Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France   Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France