Group : Salah Mecheri

Members

Salah Mecheri

Group Leader

Head

Morgane Grand

PhD Student

Roger Peronet

Technician

Former Members

Claudia Demarta-Gatsi

Sylvie Garcia

Camilla Luiza Batista

Malika Serra-Hassoun

Mishelle Waqasi

Projects

project

Ongoing

2 Members

Rodent and human malaria models to investigate host-parasite interactions central for malaria pathogenesis

Salah Mecheri (PI)

During the past few years, using a murine model for experimental cerebral malaria (ECM), we pursued our investigation regarding the contribution of the allergic inflammatory response in the pathogenesis of malaria disease. Following the […]

Transversal Project

Institut Carnot Pasteur MS

The Carnot Label Carnot label is granted to public research structures, showing high level R&I competencies dedicated to fostering innovation with industrial partners. The Carnot Institutes (IC) are funded to conduct upstream research capable […]

Publications

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• 2017
  Demarta-Gatsi C, Peronet R, Smith L, Thiberge S, Ménard R, Mécheri S, Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite, Sci Rep 2017 Aug;7(1):9129.
• 2017
  Roussilhon C, Bang G, Bastaert F, Solhonne B, Garcia-Verdugo I, Peronet R, Druilhe P, Sakuntabhai A, Mecheri S, Sallenave JM, The antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria, Sci Rep 2017 Feb;7:42243.
• 2016
  Chen PB, Ding S, Zanghì G, Soulard V, DiMaggio PA, Fuchter MJ, Mecheri S, Mazier D, Scherf A, Malmquist NA, Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites, Sci Rep 2016 Feb;6:21802.
• 2015
  Herrant M, Loucoubar C, Boufkhed S, Bassène H, Sarr FD, Baril L, Mercereau-Puijalon O, Mécheri S, Sakuntabhai A, Paul R, Risk factors associated with asthma, atopic dermatitis and rhinoconjunctivitis in a rural Senegalese cohort, Allergy Asthma Clin Immunol 2015;11(1):24.
• 2015
  Briquet S, Lawson-Hogban N, Boisson B, Soares MP, Péronet R, Smith L, Ménard R, Huerre M, Mécheri S, Vaquero C, Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity, Infect. Immun. 2015 Jul;83(7):2771-84.
• 2014
  Mathieu C, Demarta-Gatsi C, Porcherie A, Brega S, Thiberge S, Ronce K, Smith L, Peronet R, Amino R, Ménard R, Mécheri S, Plasmodium berghei histamine-releasing factor favours liver-stage development via inhibition of IL-6 production and associates with a severe outcome of disease, Cell. Microbiol. 2015 Apr;17(4):542-58.
• 2013
  Kanjarawi R, Dy M, Bardel E, Sparwasser T, Dubois B, Mecheri S, Kaiserlian D, Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis, PLoS ONE 2013;8(7):e69183.
• 2013
  Herrant M, Loucoubar C, Bassène H, Gonçalves B, Boufkhed S, Diene Sarr F, Fontanet A, Tall A, Baril L, Mercereau-Puijalon O, Mécheri S, Sakuntabhai A, Paul R, Asthma and atopic dermatitis are associated with increased risk of clinical Plasmodium falciparum malaria, BMJ Open 2013;3(7).
• 2012
  Malmquist NA, Moss TA, Mecheri S, Scherf A, Fuchter MJ, Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum, Proc. Natl. Acad. Sci. U.S.A. 2012 Oct;109(41):16708-13.
• 2012
  Li T, Bourgeois JP, Celli S, Glacial F, Le Sourd AM, Mecheri S, Weksler B, Romero I, Couraud PO, Rougeon F, Lafaye P, Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging, FASEB J. 2012 Oct;26(10):3969-79.
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Contact

Phone: +33 1 45 68 82 45 Email: salah.mecheri@pasteur.fr Address 25-28 Rue du Docteur Roux 75015, Paris France

Published on: 19 Jan 2016 • Modified on: 01 Feb 2019