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  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
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  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
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About

The team works on the underlying molecular mechanisms of the progeroid disease Cockayne syndrome and their link with physiological ageing. We focus on the role of oxidative and nitrosative stress, epigenetic alterations, and mitochondrial dysfunction in pathophysiological ageing. This disease is clinically very heterogeneous and is poorly recapitulated in animal models. For this, we study cells derived from multiple patients with different clinical severity, and patient-derived induced pluripotent stem cells (iPSCs) and cerebral organoids. We have also generated isogenic cellular models to study genotype/phenotype correlations that remain elusive to date. Our team has also experience in DNA repair.

 

Former Members

2000
2000
Name
Position
2015
2019
Group: Miria Ricchetti
2015
2019
Laurent Chatre
Permanent Researcher
2015
2019
Haser Sutcu
PhD Student

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Contact

Phone: Email: Address 25-28 Rue du Docteur Roux 75015, Paris France