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About

Our aim is to understand how the structural organization of the genome contributes and influences genomic functions and notably gene expression. We are particularly interested into the role of the 3D architecture of the genome in the regulation of developmental genes by distant cis-acting elements. We use and develop novel in vivo genomic and chromatin engineering strategies as well as functional genomics approaches to investigate and uncover the molecular determinants that translate a linear sequence into specific 3D domains and dispersed regulatory information into specific and robust gene expression programs. We are as well studying how changes in these mechanisms and genome structure contribute to animal evolution and human pathologies.

Events

Mini Symposium and Workshop – Single cell @ Pasteur

Building: Duclaux – Room: Duclaux – Address: 28 Rue du Dr Roux, 75015 Paris, France
2017-11-13 13:00:00 2017-11-13 18:00:00 Europe/Paris Mini Symposium and Workshop – Single cell @ Pasteur The aims of this Mini Symposium are to discuss the recent developments in single cell genetic and genomic technologies and present the new technological pipelines available at Pasteur to conduct such experiments. Welcome and […] 28 Rue du Dr Roux, 75015 Paris, France

Publications