Cellular Plasticity and Disease Modelling Group studies the cause and consequence of cellular plasticity in ageing and cancer.
Cellular plasticity is the ability of a cell to acquire a new identity and to adopt an alternative fate when exposed to different conditions. Recent breakthrough in nuclear reprogramming highlights the amazing plasticity of differentiated cells, which has exciting implications for advances in disease modelling and regenerative medicine.
Cellular plasticity is now emerging as an important process in normal physiology and in disease states, such as ageing and cancer. Our goal is to understand how aberrant cellular plasticity is induced during tumorigenesis and how to modulate cellular plasticity for regeneration especially in ageing related diseases.