We use biophysical experimental techniques such as crystallography and cryo-EM to visualize at the atomic level the structure of molecules essential to life, such as DNA polymerases involved in DNA Repair and Cancer and […]
Directeur de Recherche, CNRS
On the cover: Type IV pili (T4P), long and flexible appendages at the surface of many bacteria, are critical virulence factors. Pili of enterohemorrhagic E. coli (EHEC), an important human pathogen, are polymers of […]
In the Cell, Proteins and Nucleic Acid assemble into larger structures, called macromolecular complexes. These complexes are specialized biological machineries that accomplish fundamental tasks that are at the basis of life. I employ computer modeling […]
