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About

-MSc, PhD

Project Summary: I am manager of the 4-years group (G4) in Bioinformatics and Biostatistics applied to infectious diseases. As mathematician specialized in statistical genetics, my research project aims at identifying the environmental factors and the genetic factors as well as their interactions implicated in malaria and arboviral infections and in the various clinical manifestations of these diseases. The estimation of key environmental and genetic parameters contributes to better understand the emergence and maintenance of these diseases by their inclusion in the mathematical modeling of infections dynamics. Analyses of epidemiological and clinical data are being performed using generalized regression methods and data mining depending on the data design and on the distribution of the traits under study. The study of host genetic factors is conducted by the development and the application of multi-makers association methods over the whole genome. These methods are particularly suited to complex multifactorial traits, such as those related to infectious diseases These methods can include biological knowledge such as gene expression data, interactions between proteins (Pathways, Gene co-expression and protein-protein interactions networks based Genome-Wide Association Studies). The modeling of the dynamics of infections will be performed using compartmental models for vector-borne pathogens. The G4 consists of researchers specialized in biostatistics and bioinformatics working closely with local IPD’s research units for, e.g., the definition of study designs, the development of new methods and proposal of programs for data analysis.

Events

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#EUROmicroMOOC: Trends in Microbiology by Twitter

Address: Twitter
2018-10-02 17:00:00 2018-11-15 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Twitter

ComPaRe – COMmunity of PAtients for REsearch- Dr Philippe Ravaud – Philippe Ravaud

Building: François Jacob – Room: amphithéâtre François Jacob – Address: Institut Pasteur, Paris, France
2018-10-18 11:00:00 2018-10-18 12:00:00 Europe/Paris ComPaRe – COMmunity of PAtients for REsearch- Dr Philippe Ravaud Dr Philippe Ravaud is a MD-PHD in epidemiology and the director of the Centre of  Epidemiology at the Hotel-Dieu (Paris) and of the French Cochrane Centre. For more than 15 years, his primary research has […] Institut Pasteur, Paris, France

International Conference on Physics and Biological Systems, Oct 22-24 2018, Gif-sur-Yvette – Arezki Boudaoud, Giovanni Cappello, Guillaume Charras, Sarah Cuylen-Häring, Ulrike Endesfelder, Benjamin Engel, Valérie Gabelica, Gary Karpen, Laëtitia Kurzawa, Amélie Leforestier, Laura Marcu, Boris Martinac, Davide Marenduzzo, Elliot Meyerowitz, Thomas Perkins, Rob Phillips, Rudi Podgornik, Yitzhak Tor, Shelly Tzlil, TomasoZambelli

Address: CNRS Campus 1 Avenue de la Terrasse, 91190 Gif-sur-Yvette
2018-10-22 08:30:00 2018-10-24 18:15:00 Europe/Paris International Conference on Physics and Biological Systems, Oct 22-24 2018, Gif-sur-Yvette The 4th International Conference on Physics and Biological Systems PhysBio 2018 will be held on Oct 22-24 2018 in Gif-sur-Yvette. It aims to bring together a broad range of physical and life scientists working at the […] CNRS Campus 1 Avenue de la Terrasse, 91190 Gif-sur-Yvette

SYK/CARD9 dependent immunity to candida sp – Attila Gacser

Building: François Jacob – Room: auditorium François Jacob – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2018-10-22 14:00:00 2018-10-22 15:00:00 Europe/Paris SYK/CARD9 dependent immunity to candida sp – Attila Gacser Attila Gacser (University of Szeged, Department of Microbiology,Hungary) C-type lectin receptors signal through Syk and CARD9. Several major fungal pathogens activate this route in innate immune cells. Candida parapsilosis is a regular cause of […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Soutenance de Thèse : Impact of microbiota on intestinal stem cells survival after irradiation – Antonin Levy

Building: François Jacob – Room: Amphithéâtre Jacques Monod – Address: 25-28 Rue du Dr Roux, 75015 Paris, France
2018-10-31 14:00:00 2018-10-31 17:00:00 Europe/Paris Soutenance de Thèse : Impact of microbiota on intestinal stem cells survival after irradiation Soutenance de Thèse de Doctorat  de Microbiologie   Université Paris Diderot,  Ecole doctorale BioSPC 25-28 Rue du Dr Roux, 75015 Paris, France

Developmental and Stem Cell Biology Department seminar by Doctor Jochen Rink, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

Building: J.Monod (#66) – Room: Monod 7th floor, rooms 2 & 3 a+b – Address: Institut Pasteur, 25 Rue du Docteur Roux, 75015 Paris, France
2018-11-16 11:00:00 2018-11-16 12:00:00 Europe/Paris Developmental and Stem Cell Biology Department seminar by Doctor Jochen Rink, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany “Why some worms regenerate while others cannot – molecular and evolutionary mechanisms in planarian regeneration” Invited Speaker: Doctor Jochen Rink Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany   Abstract: Some […] Institut Pasteur, 25 Rue du Docteur Roux, 75015 Paris, France

CRISPR in Parasitology Symposium

Building: Duclaux – Room: Amphitheater – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2018-11-19 13:00:00 2018-11-20 13:00:00 Europe/Paris CRISPR in Parasitology Symposium The department of Parasites and Insect Vectors is pleased to host a “CRISPR in Parasitology” symposium. The goal of the meeting will be to facilitate lively discussion and sharing of information/advice about various CRISPR […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Symposium « RNA and genome stability »

Building: François Jacob – Room: Auditorium François Jacob – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2018-12-05 09:00:00 2018-12-05 18:00:00 Europe/Paris Symposium « RNA and genome stability » Invited Speakers : Peter Andersen (Institute of Molecular Biotechnology, Vienna): “Hacking gene expression: active heterochromatin in genetic conflicts” Elizabeth Bayne (University of Edinburgh): “Small RNAs and heterochromatin regulation in fission yeast” Marianne Farnebo (Karolinska Institute): “RNA-guided […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Bacterial Cell Biology – Yves Brun, Nicolas Desprat, Tam Mignot, Giulia Manina, Guy Tran Van Nhieu, Marc Erhardt, Seamus Holden, Daniel Lopez, Robert Endres, Javier Lopez-Garrido, Rut Carballido-Lopez, Teuta Pilizota

Address: Institut Pasteur 28 rue du Docteur Roux 75015 Paris
2019-01-18 09:00:00 2019-01-18 17:00:00 Europe/Paris Bacterial Cell Biology The symposium will focus on bacterial cell biology studied at the sub-cellular and single-cell levels, with an emphasis on the dynamics of cellular organization, regulation and signalling.   The meeting is organized in the […] Institut Pasteur 28 rue du Docteur Roux 75015 Paris

1st European Top-Down Proteomics Symposium (TDP2019)

Building: François Jacob – Room: Auditorium – Address: Institut Pasteur, Paris, France
2019-02-12 13:30:00 2019-02-14 14:00:00 Europe/Paris 1st European Top-Down Proteomics Symposium (TDP2019) Website of the symposium with online registration www.tdp2019.conferences-pasteur.org The symposium will focus on top-down proteomics, the analysis of intact proteins and protein complexes using high-resolution mass spectrometry. In this symposium, world-leading experts in top-down […] Institut Pasteur, Paris, France

Past events

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“Decoding toxin-parasite interactions in Trypanosomatids”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2015-10-08 17:00:00 2015-10-08 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Parasitology in the 21st century”

Building: Duclaux (01) – Room: Amphithéâtre Duclaux – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2015-11-23 17:00:00 2015-11-24 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Research on Malaria transmission stages”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2015-12-16 17:00:00 2015-12-16 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Breadth of the humoral response and antigenic targets associated with protection following experimental Plasmodium falciparum sporozoite inoculation in humans”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2015-12-17 17:00:00 2015-12-17 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Trans-splicing and RNA modification regulate the life and death of Trypanosoma brucei”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-01-07 17:00:00 2016-01-07 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“High throughput approaches to understanding Plasmodium erythrocyte invasion”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-01-21 17:00:00 2016-01-21 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Protection against malaria is induced by blood stage-arresting Histamine Releasing Factor (HRF)-deficient Plasmodium parasites”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-01-28 17:00:00 2016-01-28 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Avian malaria and the evolutionary ecology of host-parasite interactions”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-02-04 17:00:00 2016-02-04 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Scientific Day on Genome Editing Technology : CRISPR-Cas9 Seminar – James Goldmeyer, Janine Scholefield

Building: Monod (66) – Room: Amphithéâtre – Address: Institut Pasteur, Paris, France
2016-02-11 17:00:00 2016-02-11 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Paris, France

“The impact of hotspot targeted interventions on malaria transmission: an example of different scientific disciplines investigating public health solutions”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-02-18 17:00:00 2016-02-18 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Study of human hepatotropic pathogens in mice with humanized live”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-02-24 17:00:00 2016-02-24 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Establishing a road map of the developmental program leading to infectivity in African trypanosomes”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-03-17 17:00:00 2016-03-17 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Coat replacement dynamics in the African trypanosome”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-03-24 17:00:00 2016-03-24 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“P.falciparum resistance to artemisinins: who cares?”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-03-31 17:00:00 2016-03-31 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

“Insights into the B cell and Tfh cell biology underlying the inefficient acquisition of humoral immunity to malaria”

Building: Lwoff – Room: Retrovirus – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2016-04-07 17:00:00 2016-04-07 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Advancing scientific innovations with ECHO Acoustic Liquid Handling – Rosemary Burke, Stephan Lorenz, Richard Ellson

Building: Lwoff – Room: RDC-14/15 – Address: Institut Pasteur, Paris, France
2016-04-15 17:00:00 2016-04-15 18:00:00 Europe/Paris #EUROmicroMOOC: Trends in Microbiology by Twitter University of Oxford, the Institute Pasteur in Paris, Stanford University, CSIC (Spanish National Research Council), are some of the eighteen international universities and research centres which will collaborate in the first worldwide open access […] Institut Pasteur, Paris, France