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© Institut Pasteur
Cryptococcus neoformans
Publication : Journal of clinical microbiology

Use of microsatellite markers and gene dosage to quantify gene copy numbers in Candida albicans

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of clinical microbiology - 01 Mar 2005

Costa JM, Eloy O, Botterel F, Janbon G, Bretagne S

Link to Pubmed [PMID] – 15750114

J. Clin. Microbiol. 2005 Mar;43(3):1387-9

With microsatellite marker typing, the number of alleles must be known for calculation of allelic frequencies in the diploid Candida albicans for a given locus. We describe a gene dosage with a double real-time PCR. Such a dosage should also be useful in exploring the loss of heterozygosity in C. albicans.

http://www.ncbi.nlm.nih.gov/pubmed/15750114