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© Research
Publication : Journal of bacteriology

Transcriptional slippage in mxiE controls transcription and translation of the downstream mxiD gene, which encodes a component of the Shigella flexneri type III secretion apparatus

Team: Archived: Molecular Microbial Pathogenesis
Member: Claude Parsot
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of bacteriology - 01 Feb 2006

Penno C, Parsot C

Link to Pubmed [PMID] – 16428428

J. Bacteriol. 2006 Feb;188(3):1196-8

The Shigella flexneri transcription activator MxiE is produced by transcriptional slippage from two overlapping open reading frames. By using plasmids encoding a mxiD-lacZ translational fusion, we showed that transcriptional slippage in mxiE influences both transcription and translation of the downstream mxiD gene encoding an essential component of the type III secretion apparatus.