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© Research
Publication : Journal of clinical microbiology

Toxin detection in patients’ sera by mass spectrometry during two outbreaks of type A Botulism in France

Team: Archived: Anaerobe Bacteria and Toxins
Member: Michel-Robert Popoff
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of clinical microbiology - 19 Sep 2012

Mazuet C, Ezan E, Volland H, Popoff MR, Becher F

Link to Pubmed [PMID] – 22993181

J. Clin. Microbiol. 2012 Dec;50(12):4091-4

In two outbreaks of food-borne botulism in France, Clostridium botulinum type A was isolated and characterized from incriminated foods. Botulinum neurotoxin type A was detected in the patients’ sera by mouse bioassay and in vitro endopeptidase assay with an immunocapture step and identification of the cleavage products by mass spectrometry.

http://www.ncbi.nlm.nih.gov/pubmed/22993181