Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export • Research

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whocc
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Associate Professor
Clinical Research Assistant
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Visiting Scientist

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Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

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Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues

Identification Of Erythromyeloid Progenitors And Their Progeny In The Mouse Embryo By Flow Cytometry

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Diseases

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Published in - 18 Jul 2017

Grotzke JE, Kozik P, Morel JD, Impens F, Pietrosemoli N, Cresswell P, Amigorena S, Demangel C.

Link to Pubmed [PMID] – 28679634

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5910-E5919

Projects

Therapeutic potential of mycolactone and synthetic surrogates

Whether released by bacteria infecting the skin or injected via the subcutaneous route, mycolactone was found to diffuse into the leukocytes of peripheral blood and lymphoid organs. With this distribution profile, the unique effects […]

Immunity against Mycobacterium ulcerans : the subversive role of mycolactone

Mycobacterium ulcerans causes Buruli ulcer, a neglected tropical skin disease manifesting as chronic wounds that can leave victims with major, life-long deformity and disability. Differently from other mycobacteria, including the related M. tuberculosis and […]

Published on: 18 Jul 2017 • Modified on: 23 Aug 2017