Link to Pubmed [PMID] – 20107096
J. Clin. Microbiol. 2010 Apr;48(4):1478-80
We report the use of PCR techniques on a formalin-fixed and paraffin-embedded tissue specimen for direct detection of one dominant azole resistance mechanism in a case of disseminated invasive aspergillosis. Rapid detection of mutations associated with azole resistance directly in tissue significantly reduces diagnostic delay.