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© Research
Publication : Antimicrobial agents and chemotherapy

Gene heterogeneity for tetracycline resistance in Staphylococcus spp

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Antimicrobial agents and chemotherapy - 01 Aug 1990

Bismuth R, Zilhao R, Sakamoto H, Guesdon JL, Courvalin P

Link to Pubmed [PMID] – 2221873

Antimicrob. Agents Chemother. 1990 Aug;34(8):1611-4

Nucleotide sequences related to four tet genes were studied by hybridization in 183 clinical Staphylococcus isolates. tet(K) predominated in strains resistant only to tetracycline, while tet(M) was responsible for combined tetracycline and minocycline resistance. In strains harboring both genes, they contributed additively. tet(L) was detected in only five strains, and no hybridization was observed with tet(O).