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© A. Alanio, E. Perret
Prolifération de Cryptococcus neoformans dans des macrophages murins.
Publication : Transplant infectious disease : an official journal of the Transplantation Society

Failure of multiplex meningitis/encephalitis (ME) NAT during cryptococcal meningitis in solid organ recipients.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Transplant infectious disease : an official journal of the Transplantation Society - 01 Aug 2020

Pilmis B, Bougnoux ME, Guery R, Senghor Y, Le Monnier A, Lanternier F, Bretagne S, Alanio A, Lortholary O,

Link to Pubmed [PMID] – 32056348

Link to DOI [DOI] – 10.1111/tid.13263

Transpl Infect Dis 2020 Aug; 22(4): e13263

Cryptococcal meningitis is a severe cause of central nervous system infections among immunocompromised solid organ transplant (SOT) patients. While new diagnostic methods as multiplex meningitis/encephalitis (ME) NAT (nucleic acid test) are increasingly used as a first-line tool in hospital practice, data in HIV-negative patients including SOT remain scarce. We report here false-negative results of multiplex NAT among SOT patients with proven cryptococcal meningitis.

https://pubmed.ncbi.nlm.nih.gov/32056348