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© Pierre Lafaye
Astrocytes marqués par des anticorps VHH anti-GFAP. Des anticorps d'alpagas dirigés contre une protéine spécifique des astrocytes, la GFAP (Glial Fibrillary Acidic Protein), ont été obtenus à partir de camélidés immunisés. La partie VHH (partie de l'anticorps qui reconnaît l'antigène) a été exprimée sous forme recombinante chez Escherichia coli.
Publication : Cell and tissue research

Expression of alpha and beta tropomyosin subunits during early myogenesis in somites and limb buds of chick embryos

Team: Antibody Engineering
Member: Farida Nato
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell and tissue research - 01 Jun 1989

Delezoide AL, Pavlovitch JH, Nato F, Fiszman MY

Link to Pubmed [PMID] – 2743399

Cell Tissue Res. 1989 Jun;256(3):631-4

The appearance of alpha and beta subunits of skeletal tropomyosin in early myogenesis was studied histochemically using monoclonal antibody to alpha tropomyosin and affinity-purified polyclonal antibody to beta tropomyosin. In muscle cells, in both somites and limb buds, the alpha and beta subunits are simultaneously expressed and first appear in the somites at the 30-36 somites. The relatively greater amount of beta than alpha tropomyosin found in early myogenesis is thus likely to result from a higher rate of beta tropomyosin synthesis.

http://www.ncbi.nlm.nih.gov/pubmed/2743399