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© Therese Couderc, Marc Lecuit
Publication : Journal of clinical microbiology

Emergence of disseminated infections due to Geosmithia argillacea in patients with chronic granulomatous disease receiving long-term azole antifungal prophylaxis.

Team: Biology of infection
Team: Fungal Biology and Pathogenicity
Member: Marc Lecuit
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of clinical microbiology - 26 Jan 2011

Machouart M, Garcia-Hermoso D, Rivier A, Hassouni N, Catherinot E, Salmon A, Debourgogne A, Coignard H, Lecuit M, Bougnoux ME, Blanche S, Lortholary O,

Link to Pubmed [PMID] – 21270214

Link to DOI – 10.1128/JCM.02456-10

J Clin Microbiol 2011 Apr; 49(4): 1681-3

We report two cases of invasive infections due to Geosmithia argillacea, an emerging mold, in patients with chronic granulomatous disease receiving prolonged azole antifungal prophylaxis. One patient died despite receiving a combination of four antifungals, and the other developed cerebral and medullary lesions under a combination of caspofungin, posaconazole, terbinafine, and gamma interferon.