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© Research
Publication : Eukaryotic cell

α1,3 glucans are dispensable in Aspergillus fumigatus

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Eukaryotic cell - 04 Nov 2011

Henry C, Latgé JP, Beauvais A

Link to Pubmed [PMID] – 22058140

Eukaryotic Cell 2012 Jan;11(1):26-9

A triple α1,3 glucan synthase mutant of Aspergillus fumigatus obtained by successive deletions of the three α1,3 glucan synthase genes (AGS1, AGS2, and AGS3) has a cell wall devoid of α1,3 glucans. The lack of α1,3 glucans affects neither conidial germination nor mycelial vegetative growth and is compensated by an increase in β1,3 glucan and/or chitin content.