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2018Mitochondrial reactive oxygen species regulate the induction of CD8 T cells by plasmacytoid dendritic cells, Nat Commun 2018 Jun;9(1):2241.
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2018Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells., Nat Commun. 2018 Jun 8;9(1):2241.
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2018Tumor-Derived TGFβ Alters the Ability of Plasmacytoid Dendritic Cells to Respond to Innate Immune Signaling., Cancer Res. 2018 Jun 1;78(11):3014-3026.
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2018Tumor-Derived TGFβ Alters the Ability of Plasmacytoid Dendritic Cells to Respond to Innate Immune Signaling, Cancer Res. 2018 Jun;78(11):3014-3026.
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2017Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis, Mucosal Immunol 2017 Sep;10(5):1178-1189.
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2017Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Organic & Biomolecular Chemistry, 2017, 15, 114 - 123.
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2016A Universal Influenza Vaccine Can Lead to Disease Exacerbation or Viral Control Depending on Delivery Strategies, Front Immunol 2016;7:641.
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2016Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Org. Biomol. Chem. 2016 Dec;15(1):114-123.
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2016CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection, PLoS Pathog. 2016 Jul 28;12(7):e1005770. doi: 10.1371/journal.ppat.1005770..
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2016B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer, Int. J. Cancer 2016 Sep;139(6):1358-71.
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2016The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity., Cancer Immunol Immunother 2016 Mar; 65(3): 315-25.
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2015The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR, J. Am. Chem. Soc. 2015 Oct;137(39):12438-41.
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2015Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication, Cancer Res. 2015 Aug;75(16):3279-91.
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2015Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells, J. Allergy Clin. Immunol. 2015 Nov;136(5):1355-1368.e15.
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2014Decoration of outer membrane vesicles with multiple antigens by using an autotransporter approach, Appl. Environ. Microbiol. 2014 Sep;80(18):5854-65.
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2014Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses, J. Immunol. 2014 Aug;193(4):1787-98.
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2014Conventional but not plasmacytoid dendritic cells foster the systemic virus-induced type I IFN response needed for efficient CD8 T cell priming, J. Immunol. 2014 Aug;193(3):1151-61.
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2014CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus, Sci Transl Med 2014 May;6(238):238ra72.
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2014Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings, J. Infect. Dis. 2014 Aug;210(3):424-34.
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2013MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion, J. Leukoc. Biol. 2013 Aug;94(2):315-23.
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2013Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer, Cancer Immunol. Immunother. 2013 Jun;62(6):1107-22.
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2013Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses, PLoS ONE 2013;8(1):e52003.
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2013Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis, Nat. Genet. 2013 Feb;45(2):172-9.
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2012Complexes of streptavidin-fused antigens with biotinylated antibodies targeting receptors on dendritic cell surface: a novel tool for induction of specific T-cell immune responses, Mol. Biotechnol. 2012 Jul;51(3):221-32.
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2012Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice, Blood 2012 Jul;120(1):90-9.
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2012The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences, Cancer Res. 2012 Jul;72(14):3557-69.
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2012Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential, Cell Host Microbe 2012 Apr;11(4):352-63.
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2012Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores, PLoS Pathog. 2012;8(4):e1002580.
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2012Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses, Vaccine 2012 Apr;30(18):2848-58.
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2012Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation, Mol. Microbiol. 2012 Mar;83(6):1195-209.
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2012Spirituality and religion in outpatients with schizophrenia: a multi-site comparative study of Switzerland, Canada, and the United States, Int J Psychiatry Med 2012;44(1):29-52.
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2011Do personality traits matter when choosing a group therapy for early psychosis?, Psychol Psychother 2013 Mar;86(1):19-32.
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2011Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin, Int. J. Cancer 2012 Aug;131(3):641-51.
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2011The adjuvant effect of TLR agonists on CD4(+) effector T cells is under the indirect control of regulatory T cells, Eur. J. Immunol. 2011 Aug;41(8):2303-13.
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2011ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis, J. Infect. Dis. 2011 Apr;203(8):1155-64.
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2011[Evaluation of the mental condition. How are you today?], Perspect Infirm 2011 Mar-Apr;8(2):29-31.
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2010Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses, J. Biol. Chem. 2011 Mar;286(10):7797-811.
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2010Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis, Vaccine 2010 Oct;28(44):7146-54.
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2010Induction of anti-Tat neutralizing antibodies by the CyaA vector targeting dendritic cells: influence of the insertion site and of the delivery of multicopies of the dominant Tat B-cell epitope, Vaccine 2010 Oct;28(42):6930-41.
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2010Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant, Blood 2010 Nov;116(18):3526-36.
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2010Personality traits in early psychosis: relationship with symptom and coping treatment outcomes, Early Interv Psychiatry 2011 Feb;5(1):33-40.
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2010The process of recovery of people with mental illness: the perspectives of patients, family members and care providers: part 1, BMC Health Serv Res 2010;10:161.
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2010Towards a rational approach to vaccine development, Hum Vaccin 2010 Apr;6(4):292-6.
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2010Adenylate cyclase toxin translocates across target cell membrane without forming a pore, Mol. Microbiol. 2010 Mar;75(6):1550-62.
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2009Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils, Immunity 2009 Nov;31(5):761-71.
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2009Change in delusions is associated with change in “jumping to conclusions”, Psychiatry Res 2009 Dec;170(2-3):124-7.
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2009Religion and spirituality: how clinicians in quebec and geneva cope with the issue when faced with patients suffering from chronic psychosis, Community Ment Health J 2010 Feb;46(1):77-86.
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2009The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells, Cancer Res. 2009 Aug;69(16):6590-7.
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2009Developing a model of recovery in mental health, BMC Health Serv Res 2009;9:73.
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2009Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide, ChemMedChem 2009 Apr;4(4):582-7.
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2008Group cognitive behavior therapy or social skills training for individuals with a recent onset of psychosis? Results of a randomized controlled trial, J. Nerv. Ment. Dis. 2008 Dec;196(12):866-75.
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2008Immobilized cytokines as biomaterials for manufacturing immune cell based vaccines, J Biomed Mater Res A 2008 Sep;86(4):1033-40.
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2008Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation, Blood 2008 Nov;112(9):3713-22.
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2008Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis, PLoS ONE 2008;3(7):e2833.
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2008Regulatory B and T cells in infections, Microbes Infect. 2008 Jul;10(9):1030-5.
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2008Treatment by CpG or Flt3-ligand does not affect mouse susceptibility to BSE prions, J. Neuroimmunol. 2008 Jun;197(1):74-80.
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2008Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis, Schizophr. Res. 2008 Jul;102(1-3):295-302.
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2008Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP, PLoS Pathog. 2008 Feb;4(2):e33.
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2007Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system, Cancer Res. 2007 Sep;67(18):8847-55.
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2007Personality characteristics and attachment in first episode psychosis: impact on social functioning, J. Nerv. Ment. Dis. 2007 Aug;195(8):631-9.
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2007Inhibition of phagosome maturation by mycobacteria does not interfere with presentation of mycobacterial antigens by MHC molecules, J. Immunol. 2007 Aug;179(3):1825-33.
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2007Enhanced ex vivo stimulation of Mycobacterium tuberculosis-specific T cells in human immunodeficiency virus-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector, Clin. Vaccine Immunol. 2007 Jul;14(7):847-54.
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2007Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells, J. Exp. Med. 2007 May;204(5):1107-18.
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2007[New technologies for vaccine development], Med Sci (Paris) 2007 Apr;23(4):386-90.
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2007TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help, Blood 2007 Jun;109(12):5318-26.
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2007Intrusion errors in explicit memory: their differential relationship with clinical and social outcome in chronic schizophrenia, Cogn Neuropsychiatry 2007 Mar;12(2):112-27.
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2007Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN, J. Immunol. 2007 Feb;178(4):2361-9.
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2007The extra domain A from fibronectin targets antigens to TLR4-expressing cells and induces cytotoxic T cell responses in vivo, J. Immunol. 2007 Jan;178(2):748-56.
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2006Carbohydrate antigens: synthesis aspects and immunological applications in cancer, Mini Rev Med Chem 2006 Dec;6(12):1357-73.
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2006[Analysis of in vitro delivering CD8+ T epitopes by attenuated bacteria], Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2006 Nov;22(6):730-3.
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2006Fetal spleen stroma drives macrophage commitment, Development 2006 Sep;133(18):3619-28.
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2006High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection, Infect. Immun. 2006 Jun;74(6):3396-407.
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2006Do people with a first episode of psychosis differ in personality profiles?, Schizophr. Res. 2006 Jul;85(1-3):162-7.
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2006Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells, J. Virol. 2006 May;80(10):4656-63.
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2006An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis, Infect. Immun. 2006 Apr;74(4):2128-37.
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2006Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates, Vaccine 2006 Apr;24(17):3490-9.
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2006Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination, Glycobiology 2006 May;16(5):390-401.
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2006Purification of splenic dendritic cells induces maturation and capacity to stimulate Th1 response in vivo, Int. Immunol. 2006 Mar;18(3):445-52.
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2006Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence, Infect. Immun. 2006 Jan;74(1):88-98.
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2005Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells, Biochemistry 2005 Sep;44(38):12759-66.
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2005Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines, Bioconjug. Chem. 2005 Sep-Oct;16(5):1149-59.
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2005Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis, J. Virol. 2005 Aug;79(15):9872-84.
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2005Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity, J. Biol. Chem. 2005 Oct;280(40):33953-9.
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2005Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids, Infect. Immun. 2005 May;73(5):2991-8.
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2005Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs, Immunity 2005 Apr;22(4):467-77.
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2005Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system, J. Immunol. 2005 Mar;174(6):3570-9.
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2005Cross-priming of T cell responses by synthetic microspheres carrying a CD8+ T cell epitope requires an adjuvant signal, J. Immunol. 2005 Mar;174(6):3432-9.
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2005Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein, Cancer Res. 2005 Jan;65(2):641-9.
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2005[Group interventions for people with refractory psychosis], Sante Ment Que 2005;30(1):97-115.
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2004Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo, Vaccine 2004 Dec;23(5):604-14.
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2004Antigen targeting to CD11b allows efficient presentation of CD4+ and CD8+ T cell epitopes and in vivo Th1-polarized T cell priming, J. Immunol. 2004 Nov;173(10):6089-97.
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2004Recognition of mycobacterial antigens delivered by genetically detoxified Bordetella pertussis adenylate cyclase by T cells from cattle with bovine tuberculosis, Infect. Immun. 2004 Nov;72(11):6255-61.
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2004Partial activation of neonatal CD11c+ dendritic cells and induction of adult-like CD8+ cytotoxic T cell responses by synthetic microspheres, J. Immunol. 2004 Aug;173(4):2669-74.
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2004Neonatal adaptive immunity comes of age, Nat. Rev. Immunol. 2004 Jul;4(7):553-64.
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2004Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen, Bioorg. Med. Chem. Lett. 2004 Jul;14(13):3567-70.
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2004Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens, J. Infect. Dis. 2004 Jul;190(1):115-22.
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2004Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation, Blood 2004 Sep;104(6):1808-15.
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2004Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6, Infect. Immun. 2004 Apr;72(4):2170-6.
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2004The adenylate cyclase toxin from Bordetella pertussis–a novel promising vehicle for antigen delivery to dendritic cells, Int. J. Med. Microbiol. 2004 Apr;293(7-8):571-6.
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2004New tools for antigen delivery to the MHC class I pathway, Trends Immunol. 2004 Feb;25(2):92-7.
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2003Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes, Int. Immunol. 2003 Dec;15(12):1423-30.
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2003CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family, Infect. Immun. 2003 Dec;71(12):7173-7.
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2003The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization, Int. Immunol. 2003 Oct;15(10):1161-71.
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2003New approaches in vaccine development, Comp. Immunol. Microbiol. Infect. Dis. 2003 Oct;26(5-6):329-41.
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2003[In-vivo dynamic changes of antigen presenting cells infected with recombinant attenuated Salmonella typhimurium expressing green fluorescent protein], Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2003 Sep;19(5):425-7.
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2003In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway, J. Immunol. 2003 Sep;171(5):2242-50.
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2003Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain, J. Biol. Chem. 2003 Oct;278(40):38514-21.
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2003Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis, Nat. Med. 2003 May;9(5):533-9.
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2003Ontogeny and innate properties of neonatal dendritic cells, Blood 2003 Jul;102(2):585-91.
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2003The shift of Th1 to Th2 immunodominance associated with the chronicity of Mycobacterium bovis bacille Calmette-Guérin infection does not affect the memory response, J. Immunol. 2003 Feb;170(3):1392-8.
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2003CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles, Virology 2003 Jan;305(2):428-35.
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2002In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c + CD8 alpha -CD11bhigh dendritic cells., Eur J Immunol 2002 Nov; 32(11): 3071-81.
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2002Virus-like particles: a new family of delivery systems, Expert Rev Vaccines 2002 Jun;1(1):101-9.
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2002Induction of HLA-A2-restricted CTL responses by a tubular structure carrying human melanoma epitopes, Vaccine 2002 Jun;20(19-20):2463-73.
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2002CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules, J. Exp. Med. 2002 May;195(10):1233-45.
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2002Challenges and issues in new vaccine development, Trends Immunol. 2002 Apr;23(4):173-5.
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2002Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells, J. Immunol. 2002 Mar;168(5):2219-24.
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2002Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity., J Immunol 2002 Feb; 168(3): 1294-301.
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2002Delivery of a MalE CD4(+)-T-cell epitope into the major histocompatibility complex class II antigen presentation pathway by Bordetella pertussis adenylate cyclase, Infect. Immun. 2002 Feb;70(2):1002-5.
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2002Induction of protective antiviral cytotoxic T cells by a tubular structure capable of carrying large foreign sequences, Vaccine 2002 Jan;20(9-10):1369-77.
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2000Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells., Methods Enzymol 2000 ; 326(): 527-42.
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1999mAb against hen egg-white lysozyme regulate its presentation to CD4(+) T cells., Int Immunol 1999 Nov; 11(11): 1863-72.
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1999Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway., J Immunol 1999 Feb; 162(4): 1910-6.
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1998The rate of dissociation between antibody and antigen determines the efficiency of antibody-mediated antigen presentation to T cells., J Immunol 1998 Nov; 161(9): 4542-8.