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Guides
  • 2019
    Hallez C, Li X, Suspène R, Thiers V, Bouzidi MS, M Dorobantu C, Lucansky V, Wain-Hobson S, Gaudin R, Vartanian JP, Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus, Nat Microbiol 2019 07;4(7):1196-1207.
  • 2019
    Mussil B, Suspène R, Caval V, Durandy A, Wain-Hobson S, Vartanian JP, Genotoxic stress increases cytoplasmic mitochondrial DNA editing by human APOBEC3 mutator enzymes at a single cell level, Sci Rep 2019 Feb;9(1):3109.
  • 2019
    Li X, Caval V, Wain-Hobson S, Vartanian JP, Elephant APOBEC3A cytidine deaminase induces massive double-stranded DNA breaks and apoptosis, Sci Rep 2019 Jan;9(1):728.
  • 2018
    Laude HC, Caval V, Bouzidi MS, Li X, Jamet F, Henry M, Suspène R, Wain-Hobson S, Vartanian JP, The rabbit as an orthologous small animal model for APOBEC3A oncogenesis, Oncotarget 2018 Jun;9(45):27809-27822.
  • 2014
    Cachat A, Alais S, Chevalier SA, Journo C, Fusil F, Dutartre H, Boniface A, Ko NL, Gessain A, Cosset FL, Suspène R, Vartanian JP, Mahieux R, ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity, Retrovirology 2014;11:93.
  • 2014
    Caval V, Suspène R, Shapira M, Vartanian JP, Wain-Hobson S, A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3’UTR enhances chromosomal DNA damage, Nat Commun 2014;5:5129.
  • 2013
    Caval V, Suspène R, Vartanian JP, Wain-Hobson S, Orthologous mammalian APOBEC3A cytidine deaminases hypermutate nuclear DNA, Mol. Biol. Evol. 2014 Feb;31(2):330-40.
  • 2013
    Mussil B, Suspène R, Aynaud MM, Gauvrit A, Vartanian JP, Wain-Hobson S, Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death, PLoS ONE 2013;8(8):e73641.
  • 2013
    Suspène R, Aynaud MM, Vartanian JP, Wain-Hobson S, Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase, PLoS ONE 2013;8(6):e63461.
  • 2012
    Ko NL, Birlouez E, Wain-Hobson S, Mahieux R, Vartanian JP, Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1, J. Gen. Virol. 2012 Dec;93(Pt 12):2646-51.
  • 2012
    Aynaud MM, Suspène R, Vidalain PO, Mussil B, Guétard D, Tangy F, Wain-Hobson S, Vartanian JP, Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A, J. Biol. Chem. 2012 Nov;287(46):39182-92.
  • 2012
    Henry M, Terzian C, Peeters M, Wain-Hobson S, Vartanian JP, Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions, PLoS ONE 2012;7(1):e30036.
  • 2011
    Suspène R, Aynaud MM, Koch S, Pasdeloup D, Labetoulle M, Gaertner B, Vartanian JP, Meyerhans A, Wain-Hobson S, Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo, J. Virol. 2011 Aug;85(15):7594-602.
  • 2011
    Suspène R, Aynaud MM, Guétard D, Henry M, Eckhoff G, Marchio A, Pineau P, Dejean A, Vartanian JP, Wain-Hobson S, Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism, Proc. Natl. Acad. Sci. U.S.A. 2011 Mar;108(12):4858-63.
  • 2010
    Suspène R, Petit V, Puyraimond-Zemmour D, Aynaud MM, Henry M, Guétard D, Rusniok C, Wain-Hobson S, Vartanian JP, Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines, J. Virol. 2011 Mar;85(5):2458-62.
  • 2010
    Renard M, Henry M, Guétard D, Vartanian JP, Wain-Hobson S, APOBEC1 and APOBEC3 cytidine deaminases as restriction factors for hepadnaviral genomes in non-humans in vivo, J. Mol. Biol. 2010 Jul;400(3):323-34.
  • 2010
    Vartanian JP, Henry M, Marchio A, Suspène R, Aynaud MM, Guétard D, Cervantes-Gonzalez M, Battiston C, Mazzaferro V, Pineau P, Dejean A, Wain-Hobson S, Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis, PLoS Pathog. 2010 May;6(5):e1000928.
  • 2009
    Gonzalez MC, Suspène R, Henry M, Guétard D, Wain-Hobson S, Vartanian JP, Human APOBEC1 cytidine deaminase edits HBV DNA, Retrovirology 2009;6:96.
  • 2009
    Petit V, Vartanian JP, Wain-Hobson S, Powerful mutators lurking in the genome, Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2009 Mar;364(1517):705-15.
  • 2009
    Henry M, Guétard D, Suspène R, Rusniok C, Wain-Hobson S, Vartanian JP, Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G, PLoS ONE 2009;4(1):e4277.
  • 2008
    Petit V, Guétard D, Renard M, Keriel A, Sitbon M, Wain-Hobson S, Vartanian JP, Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo, J. Mol. Biol. 2009 Jan;385(1):65-78.
  • 2008
    Suspène R, Renard M, Henry M, Guétard D, Puyraimond-Zemmour D, Billecocq A, Bouloy M, Tangy F, Vartanian JP, Wain-Hobson S, Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs, Nucleic Acids Res. 2008 Jul;36(12):e72.
  • 2008
    Vartanian JP, Guétard D, Henry M, Wain-Hobson S, Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions, Science 2008 Apr;320(5873):230-3.
  • 2007
    Terzian C, Henry M, Meyerhans A, Wain-Hobson S, Vartanian JP, Induction of mutations in Drosophila melanogaster gypsy retroelements by modulation of intracellular deoxynucleoside triphosphate pools in vivo, J. Virol. 2007 May;81(9):4900-3.
  • 2006
    Suspène R, Rusniok C, Vartanian JP, Wain-Hobson S, Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication, Nucleic Acids Res. 2006;34(17):4677-84.
  • 2006
    Delebecque F, Suspène R, Calattini S, Casartelli N, Saïb A, Froment A, Wain-Hobson S, Gessain A, Vartanian JP, Schwartz O, Restriction of foamy viruses by APOBEC cytidine deaminases, J. Virol. 2006 Jan;80(2):605-14.
  • 2005
    Mahieux R, Suspène R, Delebecque F, Henry M, Schwartz O, Wain-Hobson S, Vartanian JP, Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases, J. Gen. Virol. 2005 Sep;86(Pt 9):2489-94.
  • 2005
    Suspène R, Henry M, Guillot S, Wain-Hobson S, Vartanian JP, Recovery of APOBEC3-edited human immunodeficiency virus G->A hypermutants by differential DNA denaturation PCR, J. Gen. Virol. 2005 Jan;86(Pt 1):125-9.
  • 2004
    Pineau P, Henry M, Suspène R, Marchio A, Dettai A, Debruyne R, Petit T, Lécu A, Moisson P, Dejean A, Wain-Hobson S, Vartanian JP, A universal primer set for PCR amplification of nuclear histone H4 genes from all animal species, Mol. Biol. Evol. 2005 Mar;22(3):582-8.
  • 2004
    Suspène R, Sommer P, Henry M, Ferris S, Guétard D, Pochet S, Chester A, Navaratnam N, Wain-Hobson S, Vartanian JP, APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase, Nucleic Acids Res. 2004;32(8):2421-9.
  • 2003
    Vartanian JP, Sommer P, Wain-Hobson S, Death and the retrovirus, Trends Mol Med 2003 Oct;9(10):409-13.
  • 2003
    Wain-Hobson S, Renoux-Elbé C, Vartanian JP, Meyerhans A, Network analysis of human and simian immunodeficiency virus sequence sets reveals massive recombination resulting in shorter pathways, J. Gen. Virol. 2003 Apr;84(Pt 4):885-95.
  • 2002
    Vartanian JP, Pineau P, Henry M, Hamilton WD, Muller MN, Wrangham RW, Wain-Hobson S, Identification of a hepatitis B virus genome in wild chimpanzees (Pan troglodytes schweinfurthi) from East Africa indicates a wide geographical dispersion among equatorial African primates, J. Virol. 2002 Nov;76(21):11155-8.
  • 2002
    Vartanian JP, Wain-Hobson S, Analysis of a library of macaque nuclear mitochondrial sequences confirms macaque origin of divergent sequences from old oral polio vaccine samples, Proc. Natl. Acad. Sci. U.S.A. 2002 May;99(11):7566-9.
  • 2002
    Vartanian JP, Henry M, Wain-Hobson S, Sustained G–>A hypermutation during reverse transcription of an entire human immunodeficiency virus type 1 strain Vau group O genome, J. Gen. Virol. 2002 Apr;83(Pt 4):801-5.
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