We have studied together with A. Bardin (Curie Institut) the role of Notch in the regulation of stem cell proliferation and differentiation in the adult fly gut.
A. J. Bardin, C. N. Perdigoto, T. D. Southall, A. H. Brand and F. Schweisguth (2010) Transcriptional control of stem cell maintenance in the Drosophila intestine. Development, 137, 705-714
C. N. Perdigoto, F. Schweisguth and A. J. Bardin (2011) Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine. Development, 138, 4585-4595
Andriatsilavo, M. Stefanutti, K. Siudeja, C. N. Perdigoto, B. Boumard, L. Gervais, A. Gillet-Markowska, L. Al Zouabi, F. Schweisguth, A. J. Bardin (2018) Spen limits intestinal stem cell self-renewal. PLoS Genetics, 14(11):e1007773
L. Gervais, M. van den Beek, M. Josserand, J. Salle, M. Stefanutti, C.N. Perdigoto, P. Skorski, K. Mazouni, O.J. Marshall, A.H. Brand, F. Schweisguth, A. J. Bardin (2019) Stem cell proliferation is kept in check by the chromatin regulators Kismet/CHD7/CHD8 and Trr/MLL3/4. Developmental Cell, 49, 556-573