About
The SEQ4EPI project, led by Santé publique France and the CNR Virus of Respiratory Infections, aims to support the long-term sustainability of genomic surveillance systems developed during the pandemic and prepare them for future crises by enhancing genomic surveillance activities in its various dimensions (expanding to other pathogens, developing genomic analysis tools, reinforcing epidemiological analysis capacities). The objectives of the SEQ4EPI project are :
- Ensuring the sustainability of SARS-CoV-2 genomic surveillance and integrating it into routine activities.
- Gradually expanding the systems established for SARS-CoV-2 to other pathogens with high emergence potential. This expansion will begin with other respiratory viruses (Influenza, RSV) but will not be limited to them.
In this framework, we define and implement bioinformatics methods for more effective monitoring of viral epidemics (SARS-CoV-2 and other respiratory viruses), in three directions:
- Development of tools that ensure the constant reliability of detection tools (RT-QPCR and sequencing) over the course of viral evolution;
- Development of Phylodynamic tools to estimate R0 epidemiological pameter;
- Development of a framework to detect and investigate transmission clusters.