About
Immune cells modulate CNS activities in physiology, but peripheral immune cells are rarely found in direct contact with the neural tissue. Instead, the immune cells are thought to affect the brain remotely and indirectly, from its borders, anatomical structures, which separate the CNS from the periphery. We hope to identify mechanisms of such remote immune influence by carefully dissecting cellular composition of one of the brain borders, the choroid plexus, and looking closely at immune-epithelium interactions.