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  • tool
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  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
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  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
18
Aug 2015
Status
Ongoing
Members
2
Structures
1

About

 

capture_decran_2015-02-13_a_15.37.08

 

Dengue is an important pathogen for several of the IPIN (Cambodia, Senegal, and Uruguay), as well as IP Paris. One of the most challenging problems that we are now facing is to have an early prognostic marker for severe Dengue. The severity could be due to the virus itself, previous encounters with other Dengue variants, but it could also be due to the genetics of the patient. Genome-wide association studies (GWAS) have been developed for exactly this purpose; to determine how the host genetics can dictate the infection outcome.

We are working with all the GWAS available data from our collaborators in the IPIN to apply and develop new mathematical models that uncover new unknown interactions.