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© Christelle Durand
Microscopie d'un neurone. Le marquage jaune montre les synapses.
Starting Date
17
Dec 2015
Status
Ongoing
Members
4
Structures
2

About

The neural cell-adhesion molecules contactin 5 and 6 are involved in brain development, and mutations in contactin genes confer increased risk for autism spectrum disorders (ASD).

Functional approaches including culture of cortical neurons, automated quantification of neuritogenesis, and the 3D modeling of contactins were developed to analyze the effects of deleterious mutations in contactin genes. Other aspects include the analysis of the auditory and visual defects that are observed in ASD patients.

http://dgs1cjvrbg5uo.cloudfront.net/sites/default/files/styles/archive_thumbnail_150x200_/public/highwire/biolopen/2/3.cover-source.jpg?itok=tDmdV97l