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© Christelle Durand
Microscopie d'un neurone. Le marquage jaune montre les synapses.
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
17
Dec 2015
Status
Ongoing
Members
5
Structures
2

About

The study of the morphology of dendritic spines is crucial for understanding brain’s synaptic activity. My research focuses on the morphology of dendritic spines reconstructed in 3D, and on the functional analysis (calcium imaging and electrophysiology) of human neurons derived from skin biopsies of patients with mutations in synaptic proteins. The long-term goal of this research is to characterize the molecular mechanisms that control both synaptic plasticity and underlie autism pathology.

http://www.jove.com/video/53197/three-dimensional-quantification-dendritic-spines-from-pyramidal

Fundings