Outbreak Investigation Task Force
The recent epidemics of Lassa fever in Nigeria, Ebola virus disease in West Africa, MERS-CoV in the Middle East, Yellow Fever in DRC, Angola and Brazil, avian influenza in Asia and Africa and Zika […]
Protein synthesis machinery of Trypanosomatid as a therapeutic target
Pathogenic protozoans of the trypanosomatid group still remain a major world health problem. Cycling between insect vectors and mammalian hosts, Trypanosoma cruzi is the causative agent of Chagas disease, while over 20 Leishmania species […]
Risk of reemergence of urban yellow fever in Brazil: role of the invasive mosquito Aedes albopictus
2016 – 2018 Programmes Transversaux de Recherche Risk of reemergence of urban yellow fever in Brazil: role of the invasive mosquito Aedes albopictus PI: Ricardo Lourenço-de-Oliveira (Instituto de Oswaldo Cruz, Rio de Janeiro, Brazil)
Emergency response to global threats of emerging and re-emerging pathogens
With over 125 years’ experience with infectious diseases, the Institut Pasteur and the Institut Pasteur International Network (IPIN), which is composed of 33 research institutes in 26 countries and five continents, are ideally positioned […]
Brain & Sepsis
Understanding the pathophysiology brain dysfunction during sepsis and the consequences in term of cognitive function.
LeiSHield – A new collaborative action to determine prevalence, anticipate emergence and assess urbanization of cutaneous and visceral leishmaniasis in LeishRIIP partner countries
Protozoan parasites of the genus Leishmania generate severe human diseases termed Leishmaniases. Due to their frequency and the severity of certain clinical forms, these diseases represent a major public health problem and limit the […]
Assessment and Health Economics
Description: Permanent research line Goal: Is dedicated to the study of the various aspects related to health evaluation, covering the areas of health economics and resource allocation methods in the industry; the creation of […]
Information and Communication Sciences and Health
Description: Permanent research line Goal: It is dedicated to research and critical analysis of the social circuit of knowledge, trying to understand the specificity of contexts and production processes, mediation, circulation, conservation and appropriation […]
History, Health and Science
Description: Permanent research line Goal: This line is dedicated to historical studies on the knowledge, practices, institutions and groups by which science, medicine and health are presented as social phenomena, political and cultural in […]
Non-formal education and dissemination of science and health
Description: Permanent research line Goal: Is dedicated to studies aimed at the analysis and production of science communication activities in different media, and spaces and non-formal education situations, particularly science museums, and its impact […]
Research and Diagnostics Development
Description: Permanent research line Goal: Is dedicated to studies aimed at the development and application of methodologies for the diagnosis of infectious and parasitic agents, non-communicable chronic diseases and genetic responsible for diseases of […]
Pesquisa e Desenvolvimento de Vacinas Profiláticas e Terapêuticas.
Description: Permanent research line Goal: Dedicated to studies related to prophylactic and therapeutic vaccines of interest to public health, highlighting the search for new antigens, formulations and routes of administration, as well as new […]
Clinical Research and Clinical Trials
Description: Permanent research line Goal: Oriented research to the patient, involving a person or a group of persons or the use of human material, research on disease mechanisms, therapeutic interventions or diseases, clinical trials, […]
Health and Gender, Health of the Elderly
Description: Permanent research line Goal: Is dedicated to specific studies in the area of women’s health, the man and the elderly, focusing on health promotion and gender specific health problems and diseases and the […]
Perinatal Health, Children and Adolescents
Description: Permanent research line Goal: It is dedicated to specific studies in children and adolescents considering the vulnerability and specificities of a being in growth and development, health promotion and the study of specific […]
Management of Science and Technology in Health
Description: Permanent research line Goal: Is dedicated to the study of institutional development, financing, induction and regulation of actions and ST & I products in health, and organizational innovations associated with the production of […]
Trypanosoma´s prostaglandin metabolism: role in infection, pathogenesis and drug resistance
Description: Trypanosomatids are unicellular and flagellated protozoan that parasitize a wide range of hosts. In human and animals they cause highly disabling and mortal diseases (e.g. Chagas´ disease, sleeping sickness, leishmaniasis and Nagana disease […]
Hepatitis E virus (HEV) infection among HIV-1-infected adult patients from Latin America, Southeast Asia and sub-Saharan Africa
Description: Besides major outbreaks occurring in developing countries that involve HEV genotypes 1 (1a-e) and 2 (2a-b), restricted to humans, and associated with waterborne and fecal-oral transmission, HEV genotypes 3 (3a-j) and 4 (4a-g) […]
Microbiology in Health and Environment
Description: Permanent research line Goal: Is dedicated to the study of microbiology, biochemistry, cellular and molecular biology of fungi and bacteria and their phages, protozoa and other unicellular organisms and their viruses, relevant to […]
Virology and Health
Description: Permanent research line Goal: Dedicated to apply cell biology methods, immunology and molecular biology research of viruses and viral diseases. Aims to establish the scientific basis for improving diagnosis, treatment, epidemiology and control […]
Experimental models of diseases
Description: Permanent research line Goal: Is dedicated to the development of experimental animals, in order to study the pathophysiological mechanisms and evaluation of therapeutic or prophylactic procedures. Such models involve experimental animals, cell lines […]
Entomology, Vector Biology and reservoirs of infectious agents
Description: Entomology and biodiversity; study of vectors and reservoirs of disease transmitted and its relation to the pathogens they transmit: 1 -Vector Biology and host of human and animal diseases;; 2- Taxonomy, genetics and […]
Spatio-temporal variation in pyrethroid resistance of Aedes aegypti from the cross-border region of Brazil and France: improving our knowledge on insecticide resistance dynamics.
Description: Aedes aegypti is the main vector of dengue and yellow fever viruses, diseases of major public health concern. Because no antiviral therapy or vaccine is available against dengue, reducing transmission of this disease […]
Plasmodium vivax, a major chronic malaria-causing parasite: Building a multicenter research consortium to tackle antimalarial drug resistance challenges
Description: This project aims at improving the understanding on Pv CQ resistance and particularly at identifying molecular markers associated to CQ resistance. A preliminary aspect of the work will require the implementation of technically […]
2015HIV controllers with different viral load cutoff levels have distinct virologic and immunologic profiles, J. Acquir. Immune Defic. Syndr. 2015 Apr;68(4):377-85.
2014Association of single nucleotide polymorphisms in the lens epithelium-derived growth factor (LEDGF/p75) with HIV-1 infection outcomes in Brazilian HIV-1+ individuals, PLoS ONE 2014;9(7):e101780.
2012Temporal dynamics of HIV-1 circulating subtypes in distinct exposure categories in southern Brazil, Virol. J. 2012;9:306.
2012Monitoring the emergence of resistance mutations in patients infected with HIV-1 under salvage therapy with raltegravir in Rio de Janeiro, Brazil: a follow-up study, J. Med. Virol. 2012 Dec;84(12):1869-75.
2011HIV-1 genetic diversity and drug resistance among treatment naïve patients from Southern Brazil: an association of HIV-1 subtypes with exposure categories, J. Clin. Virol. 2011 Jul;51(3):186-91.
2011The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages, Blood 2011 Mar;117(10):2944-52.
2009Near full-length genome characterization of HIV type 1 unique BC recombinant forms from Southern Brazil, AIDS Res. Hum. Retroviruses 2009 Dec;25(12):1339-44.
2009Short communication: Evidences of recent decline in the expansion rate of the HIV type 1 subtype C and CRF31_BC epidemics in southern Brazil, AIDS Res. Hum. Retroviruses 2009 Nov;25(11):1065-9.
2009Lack of primary mutations associated with integrase inhibitors among HIV-1 subtypes B, C, and F circulating in Brazil, J. Acquir. Immune Defic. Syndr. 2009 May;51(1):7-12.
2009Genetic characterization of HIV-1 BC recombinants and evolutionary history of the CRF31_BC in Southern Brazil, Infect. Genet. Evol. 2009 Jul;9(4):474-82.
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Location: Avenida Brasil, 4365 - Manguinhos, Rio de Janeiro - RJ, Brazil