Centrosome dissection of T. gondii
We propose to focus on deciphering the mechanistic underpinnings of intracellular replication, as a prominent source of pathogenesis. In particular, given its fundamental role in orchestrating central events to apicomplexan cell division, and flagellar […]
FP7 Anti-Parasitic Drug Discovery in Epigenetics (A-ParaDDisE)
We will employ a target-based strategy for the development of novel drug leads against epigenetic targets in schistosomiasis, leishmaniasis, Chagas disease and malariafocusing on key histone modifying enzymes (HME), in particular those involved in […]
Functional amyloids of the cell wall of the fungal pathogen Aspergillus fumigatus
Aspergillus fumigatus is an opportunistic pathogen than can cause a variety of diseases in immunocompromised individuals that range from allergies to severe pathologies such as invasive aspergillosis. This filamentous fungus has become the major […]
2018Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors, Cell Rep 2018 Apr;23(4):1072-1084.
2018Sex-dependent interactions between leptin, wasting and humoral immunity in two ethnic communities of school-aged children differentially exposed to Schistosoma haematobium., Trans R Soc Trop Med Hyg. 2017 Oct 1;111(10):448-456.
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