Oncobiomics – THE (heterogenity tumor ecosystem)
The Oncobiomics project is conducted in the HTE (heterogenity tumor ecosystem) national program launched by the cancer nation institute (Inca) in the third national cancer plan 2014-2019. It’s a consortium project involving 8 teams […]
Centrosome dissection of T. gondii
We propose to focus on deciphering the mechanistic underpinnings of intracellular replication, as a prominent source of pathogenesis. In particular, given its fundamental role in orchestrating central events to apicomplexan cell division, and flagellar […]
FP7 Anti-Parasitic Drug Discovery in Epigenetics (A-ParaDDisE)
We will employ a target-based strategy for the development of novel drug leads against epigenetic targets in schistosomiasis, leishmaniasis, Chagas disease and malariafocusing on key histone modifying enzymes (HME), in particular those involved in […]
Functional amyloids of the cell wall of the fungal pathogen Aspergillus fumigatus
Aspergillus fumigatus is an opportunistic pathogen than can cause a variety of diseases in immunocompromised individuals that range from allergies to severe pathologies such as invasive aspergillosis. This filamentous fungus has become the major […]
2018Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors, Cell Rep 2018 Apr;23(4):1072-1084.
2018Sex-dependent interactions between leptin, wasting and humoral immunity in two ethnic communities of school-aged children differentially exposed to Schistosoma haematobium., Trans R Soc Trop Med Hyg. 2017 Oct 1;111(10):448-456.
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