Outbreak Investigation Task Force
The recent epidemics of Lassa fever in Nigeria, Ebola virus disease in West Africa, MERS-CoV in the Middle East, Yellow Fever in DRC, Angola and Brazil, avian influenza in Asia and Africa and Zika […]
CHART: Bacterial Acquisition Routes In Neonates
Children’s Antibiotic Resistance colonization and Route of Transmission. The aim of this program is to assess the transmission of enterobacteria resistant to 3rd generation cephalosporines (EBRCIIIG) in hospitalized neonates in two low income countries […]
MITICA: Identifying the mechanisms of acquisition of a dysbiotic microbiota and pediatric environmental enteropathy in infants in the context of chronic malnutrition
Undernutrition contributes to more than 40% of the global child mortality rate. In 2014 stunting, which is the main manifestation of chronic undernutrition, affected 159 million children. Stunting entails long-term repercussions for the child, […]
Phylogenomics of Shiga’s epidemic dysentery bacillus (Shigella dysenteriae type 1)
The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]
Enterovirus A 71 (EV-A71) is an emerging pathogen that is circulating worldwide and mostly causes hand, foot, and mouth disease (HFMD) in children. However, in many cases, EV-A71 causes neurological complications, such as meningitis, […]
Hepatitis B in Burkina Faso and Central African Republic
As a follow-up to ANRS funding for a feasibility study (ANRS 12232), I received in 2011 funding from ANRS for an in-depth anthropological study of hepatitis B and vaccination in Bobo Dioulasso and the […]
TORCADIA : Epidemiology of severe childhood diarrhea: A case control study in the Central African Republic (CAR)
(Collaborators: Sébastien Breurec, Ionela Gouandjika,Thierry Frank, Caroline Martin (IP Bangui), Petulla bata, Jean Gody (Complexe pédiatrique Bangui), Tamara Giles-Vernick, Loic chartier, Muriel Vray (IP Paris)). Funding : The fondation Total. Diarrhea ranks as the […]
MACOMBA : Pragmatic clinical trial comparing a prophylactic treatment of cotrimoxazole (CTX) with sulfadoxine-pyriméthamine (SP) for malaria among pregnant women infected with HIV in Bangui
(Collaborators: Alexandre Manirakiza, Sandrine Moussa, Aude Boulay, Olga Sakanga, Sébastien Breurec, Mirdad Kazanji(IP Bangui), Lenaig Le-Fouler, Muriel Vray (IP Paris)). Funding : Fondation de France. Accounting for HIV serological status in patients is critically […]
Alerting and Surveillance for Infectious Disease Epidemics
In a context of increasing globalization of trade, the growth in international flows of travelers and goods fuels the spread of infectious diseases. The need for a global alert and response network for infectious diseases […]
2018Identifying the etiology and pathophysiology underlying stunting and environmental enteropathy: study protocol of the AFRIBIOTA project., BMC Pediatr. 2018 Jul 19;18(1):236.
2018Serotype Distribution and Antimicrobial Resistance of Shigella Species in Bangui, Central African Republic, from 2002 to 2013., Am J Trop Med Hyg. 2018 Aug;99(2):283-286..
2018Genetic Characterization of Enterovirus A71 Circulating in Africa, Emerg Infect Dis. 2018;24(4):754-757.
2017Factors associated with stunting in healthy children aged 5 years and less living in Bangui (RCA), PLoS One. 2017 Aug 10;12(8):e0182363.
2012Molecular characterization of human enteroviruses in the Central African Republic: uncovering wide diversity and identification of a new human enterovirus A71 genogroup, J. Clin. Microbiol. 2012 May;50(5):1650-8.
2008Characterization of the genome of human enteroviruses: design of generic primers for amplification and sequencing of different regions of the viral genome, J. Virol. Methods 2008 May;149(2):277-84.
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Location: B.P. 923 Bangui Central African Republic