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Symbiotic microbiota and the development and regulation of the immune system
Gérard Eberl (PI)
The symbiotic microbiota plays an essential role at many levels of host physiology, and germfree mice develop a large number of defects. In the intestine, the microbiota metabolises nutrients and toxins to generate an […]
2019Nod2 protects the gut from spreading experimental colitis to small intestine, J Crohns Colitis 2019 Nov;.
2018NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated Carcinogenesis, Cell Mol Gastroenterol Hepatol 2019;7(2):357-369.
2017GAPs in early life facilitate immune tolerance, Sci Immunol 2017 12;2(18).
2017Complementary Roles of Nod2 in Hematopoietic and Nonhematopoietic Cells in Preventing Gut Barrier Dysfunction Dependent on MLCK Activity, Inflamm. Bowel Dis. 2017 07;23(7):1109-1119.
2017Nutritional strategies and gut microbiota composition as risk factors for necrotizing enterocolitis in very-preterm infants, Am. J. Clin. Nutr. 2017 Sep;106(3):821-830.
2017Nod2: The intestinal gate keeper, PLoS Pathog. 2017 Mar;13(3):e1006177.
2016Nod2 Deficiency Leads to a Specific and Transmissible Mucosa-associated Microbial Dysbiosis Which Is Independent of the Mucosal Barrier Defect, J Crohns Colitis 2016 Dec;10(12):1428-1436.
2016Respective Roles of Hematopoietic and Nonhematopoietic Nod2 on the Gut Microbiota and Mucosal Homeostasis, Inflamm. Bowel Dis. 2016 Apr;22(4):763-73.
2015Pseudomonas fluorescens alters the intestinal barrier function by modulating IL-1β expression through hematopoietic NOD2 signaling, Inflamm. Bowel Dis. 2015 Mar;21(3):543-55.
2013Pseudomonas fluorescens can induce and divert the human β-defensin-2 secretion in intestinal epithelial cells to enhance its virulence, Arch. Microbiol. 2013 Mar;195(3):189-95.
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