Candice did a PhD on bioinorganic chemistry at the University of Hong Kong, Hong Kong, under the supervision of Prof. Hongzhe SUN, focusing on the development of fluorescence-based methodology for studying metal-binding proteins and for the elucidation of the molecular mechanism of bismuth-based antimicrobials against Helicobacter pylori infection. With an interests to continue understanding bacterial infections in a cellular context, she joined the group of Jost Enninga in May 2016. Candice will focus on the molecular events during Shigella infections and the cytosolic escape of the pathogen.
2020Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape., PLoS Pathog 2020 08; 16(8): e1008822.
2020Transcytosis subversion by M cell-to-enterocyte spread promotes Shigella flexneri and Listeria monocytogenes intracellular bacterial dissemination, PLoS Pathog. 2020 Apr;16(4):e1008446.